[1] CHOE S S, HUH J Y, HWANG I J, et al.Adipose tissue remodeling:its role in energy metabolism and metabolic disorders[J]. Front Endocrinol(Lausanne), 2016, 7:30.
[2] SPOTO B, DI BETTA E, MATTACE-RASO F, et al.Pro-and anti-inflammatory cytokine gene expression in subcutaneous and visceral fat in severe obesity[J]. Nutr Metab Cardiovasc Dis, 2014, 24(10):1137-1143.
[3] ALEXOPOULOS N, KATRITSIS D, RAGGI P.Visceral adipose tissue as a source of inflammation and promoter of atherosclerosis[J]. Atherosclerosis, 2014, 233(1):104-112.
[4] IANTORNO M, CAMPIA U, DI DANIELE N, et al.Obesity, inflammation and endothelial dysfunction[J]. J Biol Regul Homeost Agents, 2014, 28(2):169-176.
[5] 张亚娟, 范璟, 叶伟, 等.两种人外周血单核细胞来源树突状细胞表型及功能比较[J]. 现代医学, 2017, 45(2):169-174.
[6] CHO K W, ZAMARRON B F, MUIR L A, et al.Adipose tissue cendritic cells are independent contributors to obesity-Induced inflammation and insulin resistance[J]. J Immunol, 2016, 197(9):3650-3661.
[7] MILLER J C, BROWN B D, SHAY T, et al.Deciphering the transcriptional network of the dendritic cell lineage[J]. Nat Immunol, 2012, 13(9):888-899.
[8] HERNÁNDEZ-GARCÍA E, CUETO F J, COOK E C L, et al.Conventional type 1 dendritic cells protect against age-related adipose tissue dysfunction and obesity[J]. Cell Mol Immunol, 2022, 19(2):260-275.
[9] HILDRETH A D, PADILLA E T, GUPTA M, et al.Adipose cDC1s contribute to obesity-associated inflammation through STING-dependent IL-12 production[J]. Nat Metab, 2023, 5(12):2237-2252.
[10] NOUBADE R, MAJRI-MORRISON S, TARBELL K V.Beyond cDC1:emerging roles of DC crosstalk in cancer immunity[J]. Front Immunol, 2019, 10:1014.
[11] BERTOLA A, CIUCCI T, ROUSSEAU D, et al.Identification of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 responses in mice and patients[J]. Diabetes, 2012, 61(9):2238-2247.
[12] STEFANOVIC-RACIC M, YANG X, TURNER M S, et al.Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+cells in adipose tissue and liver[J]. Diabetes, 2012, 61(9):2330-2339.
[13] CHEN Y, TIAN J, TIAN X, et al.Adipose tissue dendritic cells enhances inflammation by prompting the generation of Th17 cells[J]. PLoS One, 2014, 9(3):e92450.
[14] LUMENG C N, BODZIN J L, SALTIEL A R.Obesity induces a phenotypic switch in adipose tissue macrophage polarization[J]. J Clin Invest, 2007, 117(1):175-184.
[15] RUSSO L, LUMENG C N.Properties and functions of adipose tissue macrophages in obesity[J]. Immunology, 2018, 155(4):407-417.
[16] MUIR L A, CHO K W, GELETKA L M, et al.Human CD206+macrophages associate with diabetes and adipose tissue lymphoid clusters[J/OL]. JCI Insight, 2022, 7(3):e146563.doi:10.1172/jci.insight.146563.
[17] IVANOV S, SCALLAN J P, KIM K W, et al.CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability[J]. J Clin Invest, 2016, 126(4):1581-1591.
[18] SATPATHY A T, KC W, ALBRING J C, et al.Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages[J]. J Exp Med, 2012, 209(6):1135-1152.
[19] SUNDARA RAJAN S, LONGHI M P.Dendritic cells and adipose tissue[J]. Immunology, 2016, 149(4):353-361.
[20] HILDRETH A D, MA F, WONG Y Y, et al.Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity[J]. Nat Immunol, 2021, 22(5):639-653.
[21] HATA M, ANDRIESSEN E, HATA M, et al.Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation[J]. Science, 2023, 379(6627):45-62.
[22] SILVA H M, BÁFICA A, RODRIGUES-LUIZ G F, et al.Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges[J]. J Exp Med, 2019, 216(4):786-806.
[23] FERRANTE A W Jr.The immune cells in adipose tissue[J]. Diabetes Obes Metab, 2013, 15 Suppl 3(3):34-38.
[24] WEINSTOCK A, BROWN E J, GARABEDIAN M L, et al.Single-cell RNA sequencing of visceral adipose tissue leukocytes reveals that caloric restriction following obesity promotes the accumulation of a distinct macrophage population with features of phagocytic cells[J/OL]. Immunometabolism, 2019, 1:e190008.doi:10.20900/immunometab20190008.
[25] MAJDOUBI A, KISHTA O A, THIBODEAU J.Role of antigen presentation in the production of pro-inflammatory cytokines in obese adipose tissue[J]. Cytokine, 2016, 82:112-121.
[26] FAN H, MENG W, KILIAN C, et al.Domain-specific N-glycosylation of the membrane glycoprotein dipeptidylpeptidase Ⅳ(CD26) influences its subcellular trafficking, biological stability, enzyme activity and protein folding[J]. Eur J Biochem, 1997, 246(1):243-251.
[27] ZHONG J, RAO X, DEIULIIS J, et al.A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation[J]. Diabetes, 2013, 62(1):149-157.
[28] GHOSH A R, BHATTACHARYA R, BHATTACHARYA S, et al.Adipose recruitment and activation of plasmacytoid dendritic cells fuel metaflammation[J]. Diabetes, 2016, 65(11):3440-3452.
[29] LU J, ZHAO J, MENG H, et al.Adipose tissue-resident immune cells in obesity and type 2 diabetes[J]. Front Immunol, 2019, 10:1173.
[30] LIU B, QIN Z, CAI Z, et al.Evaluating the causal association between inflammatory bowel disease and risk of atherosclerotic cardiovascular disease:univariable and multivariable mendelian randomization study[J]. Biomedicines, 2023, 11(9):2543.
[31] PAMIR N, LIU N C, IRWIN A, et al.Granulocyte/macrophage colony-stimulating factor-dependent dendritic cells restrain lean adipose tissue expansion[J]. J Biol Chem, 2015, 290(23):14656-14667.
[32] KINGSTON D, SCHMID M A, ONAI N, et al.The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis[J]. Blood, 2009, 114(4):835-843.
[33] HUDAK C S, SUL H S.Pref-1, a gatekeeper of adipogenesis[J]. Front Endocrinol(Lausanne), 2013, 4:79.
[34] O'SULLIVAN T E, RAPP M, FAN X, et al.Adipose-resident group 1 innate lymphoid cells promote obesity-associated insulin resistance[J]. Immunity, 2016, 45(2):428-441.
[35] WANG H, SHEN L, SUN X, et al.Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity[J]. Nat Commun, 2019, 10(1):3254.
[36] PATSOURIS D, LI P P, THAPAR D, et al.Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals[J]. Cell Metab, 2008, 8(4):301-309.
[37] HAMADE H, STAMPS J T, STAMPS D T, et al.BATF3 protects against metabolic syndrome and maintains intestinal epithelial homeostasis[J]. Front Immunol, 2022, 13:841065.
[38] KIM D H, SANDOVAL D, REED J A, et al.The role of GM-CSF in adipose tissue inflammation[J]. Am J Physiol Endocrinol Metab, 2008, 295(5):E1038-E1046.
[39] DARRASSE-JèZE G, DEROUBAIX S, MOUQUET H, et al.Feedback control of regulatory T cell homeostasis by dendritic cells in vivo[J]. J Exp Med, 2009, 206(9):1853-1862.
[40] MCKENNA H J, STOCKING K L, MILLER R E, et al.Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells[J]. Blood, 2000, 95(11):3489-3497.
[41] SCHWARTZ C, SCHMIDT V, DEINZER A, et al.Innate PD-L1 limits T cell-mediated adipose tissue inflammation and ameliorates diet-induced obesity[J]. Sci Transl Med, 2022, 14(635):eabj6879.
[42] LEE Y S, WOLLAM J, OLEFSKY J M.An integrated view of immunometabolism[J]. Cell, 2018, 172(1-2):22-40.
[43] JACKS R D, LUMENG C N.Macrophage and T cell networks in adipose tissue[J]. Nat Rev Endocrinol, 2024, 20(1):50-61.
[44] PENNOCK N D, WHITE J T, CROSS E W, et al.T cell responses:naive to memory and everything in between[J]. Adv Physiol Educ, 2013, 37(4):273-283.
[45] SHOKOPLES B G, PARADIS P, SCHIFFRIN E L.Immunological insights into hypertension:unraveling triggers and potential therapeutic avenues[J]. Hypertens Res, 2024, 47(8):2115-2125.
[46] WINER S, CHAN Y, PALTSER G, et al.Normalization of obesity-associated insulin resistance through immunotherapy[J]. Nat Med, 2009, 15(8):921-929.
[47] VASANTHAKUMAR A, CHISANGA D, BLUME J, et al.Sex-specific adipose tissue imprinting of regulatory T cells[J]. Nature, 2020, 579(7800):581-585.
[48] MOLOFSKY A B, NUSSBAUM J C, LIANG H E, et al.Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages[J]. J Exp Med, 2013, 210(3):535-549.
[49] WU D, MOLOFSKY A B, LIANG H E, et al.Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis[J]. Science, 2011, 332(6026):243-247.
[50] SCHWARTZ C, KHAN A R, FLOUDAS A, et al.ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control[J]. J Exp Med, 2017, 214(9):2507-2521.
[51] FRANCISCO L M, SALINAS V H, BROWN K E, et al.PD-L1 regulates the development, maintenance, and function of induced regulatory T cells[J]. J Exp Med, 2009, 206(13):3015-3029.
[52] MCALEES J W, LAJOIE S, DIENGER K, et al.Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma[J]. Eur J Immunol, 2015, 45(4):1019-1029.
[53] MCLAUGHLIN T, LIU L F, LAMENDOLA C, et al.T-cell profile in adipose tissue is associated with insulin resistance and systemic inflammation in humans[J]. Arterioscler Thromb Vasc Biol, 2014, 34(12):2637-2643.
[54] MACDOUGALL C E, WOOD E G, LOSCHKO J, et al.Visceral adipose tissue immune homeostasis is regulated by the crosstalk between adipocytes and dendritic cell subsets[J]. Cell Metab, 2018, 27(3):588-601.e4.
[55] SATOH M, IWABUCHI K.Contribution of NKT cells and CD1d-expressing cells in obesity-associated adipose tissue inflammation[J]. Front Immunol, 2024, 15:1365843.
[56] SATOH M, IIZUKA M, MAJIMA M, et al.Adipose invariant NKT cells interact with CD1d-expressing macrophages to regulate obesity-related inflammation[J]. Immunology, 2022, 165(4):414-427.
[57] YU L, LI Y, DU C, et al.Pattern recognition receptor-mediated chronic inflammation in the development and progression of obesity-related metabolic diseases[J]. Mediators Inflamm, 2019, 2019:5271295.
[58] CHAVAKIS T, ALEXAKI V I, FERRANTE A W Jr.Macrophage function in adipose tissue homeostasis and metabolic inflammation[J]. Nat Immunol, 2023, 24(5):757-766.
[59] MICHAILIDOU Z, GOMEZ-SALAZAR M, ALEXAKI V I.Innate immune cells in the adipose tissue in health and metabolic disease[J]. J Innate Immun, 2022, 14(1):4-30.
[60] HAN J M, LEVINGS M K.Immune regulation in obesity-associated adipose inflammation[J]. J Immunol, 2013, 191(2):527-532.
[61] LACKEY D E, OLEFSKY J M.Regulation of metabolism by the innate immune system[J]. Nat Rev Endocrinol, 2016, 12(1):15-28.
[62] CHUNG K J, NATI M, CHAVAKIS T, et al.Innate immune cells in the adipose tissue[J]. Rev Endocr Metab Disord, 2018, 19(4):283-292.
[63] DEN BROK M H, RAAIJMAKERS T K, COLLADO-CAMPS E, et al.Lipid droplets as immune modulators in myeloid cells[J]. Trends Immunol, 2018, 39(5):380-392.
[64] IBRAHIM J, NGUYEN A H, REHMAN A, et al.Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver[J]. Gastroenterology, 2012, 143(4):1061-1072.
[65] TRAN K V, GEALEKMAN O, FRONTINI A, et al.The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells[J]. Cell Metab, 2012, 15(2):222-229.
[66] HONG K Y, BAE H, PARK I, et al.Perilipin+embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion[J]. Development, 2015, 142(15):2623-2632. |
