[1] SIEGEL R L,MILLER K D,WAGEL N S,et al.Cancer statistics,2023[J].CA-Cancer J Clin,2023,73(1):17-48.
[2] SIKORSKI J,MATCZUK M,STEPIEN M,et al.Fe3O4 SPIONs in cancer theranostics-structure versus interactions with proteins and methods of their investigation[J].Nanotechnology,2024,35:212001.
[3] ARUNACHALAM A,ZHANG I,ZHAO B,et al.Efficacy and safety of treatments for advanced thymic carcinoma after failure of first-line platinum-based chemotherapy:a systematic literature review and meta-analysis[J]. Lung Cancer,2023,176:132-139.
[4] YUAN R,HOU Y,SUN W,et al.Natural products to prevent drug resistance in cancer chemotherapy:a review[J],Ann NY Acad Sci, 2017,1401(1):19-27.
[5] 邓莎,李梦园,武小玲,等.蟾酥化学成分及抗肿瘤作用研究进展[J].中成药,2022,44(3):884-890.
[6] LAURA S,GHANEM E,GHANEM S S,et al.Bufalin for an innovative therapeutic approach against cancer[J].Pharmacol Res,2022,184:106442.
[7] 贾彩云,石贞玉,呼文亮,等.蟾蜍灵对K562细胞凋亡诱导作用及bcl-2基因表达的影响[J].河南职工医院学报,2013,25(5):537-540.
[8] 贾彩云,王艳鸽,呼文亮,等.蟾蜍灵对白血病K562细胞生长抑制机制[J].河南大学学报(医学版),2013,32(2):129-133.
[9] SHIH Y L,CHOU J S,CHEN Y L,et al.Bufalin enhances immune responses in leukemic mice through enhancing phagocytosis of macrophage in vivo[J]. In Vivo,2018,32(5):1129-1136.
[10] 连小赟,魏旭仓,赵园,等.蟾蜍灵联合伊马替尼对K562细胞的凋亡诱导作用[J].陕西医学杂志,2013,42(10):1295-1296.
[11] SIEGEL R L,MILLER K D,FUCHS H E,et al.Cancer statistics,2022[J].CA-Cancer J Clin,2022,72(1):7-33.
[12] 朱志图,郁云龙,王锴,等.蟾蜍灵对人非小细胞肺癌A549细胞增殖与凋亡的影响[J].中国肺癌杂志,2010,13(9):841-845.
[13] WU S H,BAU D T,HSIAO Y T,et al.Bufalin induces apoptosis in vitro and has antitumor activity against human lung cancer xenografts in vivo[J].Environ Toxicol,2017,32(4):1305-1317.
[14] KUO J Y,LIAO C L,MA Y S,et al.Combination treatment of sorafenib and bufalin induces apoptosis in NCI-H292 human lung cancer cells in vitro[J].In Vivo,2022,36:582-595.
[15] HUANG A C,YANG M D,HSIAO Y T,et al.Bufalin inhibits gefitinib resistant NCI-H460 human lung cancer cell migration and invasion in vitro[J].J Ethnopharmacol,2016,194:1043-1050.
[16] SUNG H,FERLAY J,SIEGEL R L,et al.Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA-Cancer J Clin,2021,71:209-249.
[17] QI X,LIU Y,WANG W,et al.Management of advanced gastric cancer:an overview of major findings from meta-analysis[J].Oncotarget,2016,7:78180-78205.
[18] 宫鹏超,李艳兰,孔翠翠,等.蟾蜍灵通过程序性坏死途径诱导人胃癌细胞SGC-7901死亡[J].首都医科大学学报,2019,40(2):251-256.
[19] WANG J,CAI H,XIA Y,et al.Bufalin inhibits gastric cancer invasion and metastasis by down-regulating Wnt/ASCL2 expression[J].Oncotarget,2018,9:23320-23333.
[20] ZHAO H,ZHAO D,JIN H,et al.Bufalin reverses intrinsic and acquired drug resistance to cisplatin through the AKT signaling pathway in gastric cancer cells[J].Mol Med Rep,2016,14:1817-1822.
[21] RUSTGI A K,EL-SERAG H B.Esophageal carcinoma[J].New Engl J Med,2014,371:2499-2509.
[22] 田昕,罗颖,闫永波,等.蟾蜍灵对人食管鳞癌EC9706细胞增殖及凋亡的影响[J].中国医学科学院学报,2012,34(6):556-562.
[23] 李恩泽,刘阳阳,王锴,等.蟾蜍灵对食管癌ECAl09细胞凋亡的影响及机制探讨[J].军医进修学院学报,2012,33(4):393-395.
[24] LIU Y,WANG X,JIA Y,et al.Effects of bufalin on the MTOR/P70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice[J].Int J Mol Med,2017,40:357-366.
[25] 田志辉,张培,曹彦坤,等.蟾蜍灵抑制食管癌细胞增殖、迁移和趋化运动的机制研究[J].中国现代医学杂志,2015,25(20):45-49.
[26] 丁妍,王小玲,邓会岩,等.蟾蜍灵抑制Raf/MEK/细胞外信号调节激酶信号通路活化影响人食管鳞癌细胞增殖及迁移机制研究[J].中国全科医学,2015,18(21):2535-2541.
[27] BENGTSSON A,ANDERSSON R,ANSARI D.The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data[J].Sci Rep-UK,2020,10:16425.
[28] LIU X,XIAO X Y,SHOU Q Y,et al.Bufalin inhibits pancreatic cancer by inducing cell cycle arrest via the c-Myc/NF-κB pathway[J].J Ethnopharmacol,2016,193:538-545.
[29] TIAN X,DAI S,SUN J,et al.Bufalin induces mitochondria-dependent apoptosis in pancreatic and oral cancer cells by downregulating hTERT expression via activation of the JNK/p38 pathway[J].Evid-based Compl Alt,2015,2015:546210.
[30] WANG H,NING Z,LI Y,et al.Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling[J].Mol Med Rep,2016,14:1907-1914.
[31] ZHANG W,FAN Y,ZHANG J,et al.Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer[J].Drug Resist Update,2023,71:101005.
[32] FERLAY J,COLOMBET M,SOERJOMATARAM I,et al.Estimating the global cancer incidence and mortality in 2018:GLOBOCAN sources and methods[J].Int J Cancer,2021,144:1941-1953.
[33] RUMGAY H,ARNOLD M,FERLAY J,et al.Global burden of primary liver cancer in 2020 and predictions to 2040[J].J Hepatol,2022,77:1598-1606.
[34] FU R,YU F,WU W,et al.Bufalin enhances the killing efficacy of NK cells against hepatocellular carcinoma by inhibiting MICA shedding[J].Int Immunopharmacol,2021,101:108195.
[35] YE M,TANG Y,HE J,et al.Alisol B 23-acetate increases the antitumor effect of bufalin on liver cancer through inactivating wnt/β-catenin axis[J].Comput Math Method M,2022,6249534.
[36] WANG H,ZHANG C,CHI H,et al.Synergistic anticancer effects of bufalin and sorafenib by regulating apoptosis associated proteins[J].Mol Med Rep,2018,17:8101-8110.
[37] WANG H,ZHANG C,CHI H,et al.Synergistic anti-hepatoma effect of bufalin combined with sorafenib via mediating the tumor vascular microenvironment by targeting mTOR/VEGF signaling[J].Int J Oncol,2018,52:2051-2060.
[38] XU Y,LIU Y,LIU Q,et al.Co-delivery of bufalin and nintedanib via albumin sub-microspheres for synergistic cancer therapy[J].J Control Release,2021,338:705-718.
[39] 扎拉嘎胡,刘英富,兰晓霞,等.蟾蜍灵对B16细胞增殖及凋亡的影响[J].肿瘤防治研究,2014,41(10):1078-1081.
[40] GU R,ZHANG Q.Effects of low-dose bufalin combined with hydroxycamptothecin on human castration-resistant prostate cancer xenografts in nude mice[J].Exp Ther Med,2021,22:1015.
[41] 李蓉,韩香,徐忠伟,等.蟾蜍灵对EAhy926细胞增殖、凋亡及Caspase3、Bcl-2表达的影响[J].武警后勤学院学报(医学版),2012,41(2):77-80.
[42] 张云华,范志青.卵巢子宫内膜异位囊肿组织中Bax、Bcl-2蛋白表达与超声引导下聚桂醇介入术后复发的关系分析[J].现代医学,2022,50(1):47-52.
[43] 彭琪,张永利,周立霞.神经生长因子联合曲安奈德减轻缺血再灌注视网膜视神经节细胞损伤的研究[J].现代医学,2022,50(7):816-821.
[44] LINGHU H R,LUO H,GANG L.Bufalin induces glioma cell death by apoptosis or necroptosis[J].OncoTargets Ther,2020,13:4767-4778. |