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卵巢子宫内膜异位症恶变的相关研究进展
作者:郭婕莹1  蔡云朗2 
单位:1. 东南大学医学院, 江苏 南京 210009;
2. 东南大学附属中大医院妇产科, 江苏 南京 210009
关键词:卵巢子宫内膜异位症 卵巢癌 恶变 综述 
分类号:R711.75
出版年·卷·期(页码):2024·43·第一期(147-151)
摘要:

子宫内膜异位症(endometriosis,EMs)是一种慢性激素依赖性妇科疾病,影响6%~10%的育龄期妇女,对其日常生活质量产生了巨大影响。EMs良性病灶可恶变成为恶性组织,临床上称为子宫内膜异位症相关卵巢癌(endometriosis associated ovarian carcinoma,EAOC)。国内外研究表明,EAOC发病机制复杂,类固醇激素作用、炎症反应与免疫应答、氧化应激、基因突变、表观遗传学改变等多种机制参与EMs恶变过程。本文作者就EMs恶变发生的机制及其临床特点的研究进展作一综述。

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