Objective: To explore and analyze the effects of health management of medical treatment alliance model on cardiac function in patients with chronic heart failure from the perspective of health ecology. Methods: From November 2020 to February 2021, experimental communities and control communities were selected from the technical radiation community health service center of a Grade-A hospital in Nanjing by coin toss, and chronic heart failure patients meeting the exclusion criteria were recruited in the jurisdiction of the two centers as study objects.They were divided into the experimental group(n=115) and the control group(n=103). The experimental group adopted the health management mode of medical treatment alliance from the perspective of health ecology, and the control group adopted the health management education. The intervention period was 12 months, and the changes of cardiac function before and after intervention were compared. Results: Before intervention, there was no significant difference between the two groups(P>0.05). After intervention, left ventricular ejection fraction, peak mitral ring diastolic motion velocity and 6 min walking test results of experimental group were increased by 0.049 %, 0.01 cm·s^-1 and 19.669 m compared with control group, and left ventricular diameter was decreased by 0.304 mm compared with control group,the differences were statistically significant(P<0.05), and the readmission rate was significantly lower than that of the control group(χ²=6.524,P<0.05). Before and after intervention, the left ventricular diameter of the experimental group was decreased by 0.155 mm and the left ventricular ejection fraction was increased by 0.032 %, while the left ventricular diameter was increased by 0.123 mm and the left ventricular ejection fraction was decreased by 0.026% in the control group, with statistical significance(P<0.05). The peak mitral ring diastolic motion velocity and 6 min walking test results in the experimental group were increased by 0.008 cm·s^-1 and 25.669 m, the differences were statistically significant(P<0.05), and the readmission rate was changed(χ²=6.179,P<0.05), while the changes in the control group were not statistically significant(P>0.05). There were statistically significant differences in left ventricular diameter, left ventricular ejection fraction, peak mitral ring diastolic motion velocity, 6 min walking test results and time effect of readmission rate, inter group effect analysis, and interaction effect of time and intergroup between the two groups(P<0.05). Conclusion: The health management of the medical treatment alliance model from the perspective of health ecology can improve the cardiac function of patients with chronic heart failure and reduce the readmission rate.