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恶性腹水与卵巢癌转移、耐药相关性研究进展
作者:吴怡楠  徐友娣  李玉娟 
单位:南京医科大学附属南京医院(南京市第一医院) 妇产科, 江苏 南京 210006
关键词:恶性腹水 卵巢癌 信号分子 肿瘤转移 肿瘤耐药 综述 
分类号:R737.31
出版年·卷·期(页码):2023·42·第二期(324-329)
摘要:

腹腔内液体的异常积聚称为腹水,恶性肿瘤引起的腹水称为恶性腹水。卵巢肿瘤是常见的妇科肿瘤,其中卵巢恶性肿瘤起病隐匿,晚期缺乏有效治疗手段,因此致死率高居妇科恶性肿瘤之首。临床上最常见的卵巢恶性肿瘤为卵巢上皮癌,其病情进展至晚期常出现恶性腹水。恶性腹水中包含大量细胞与非细胞成分,可通过多种途径影响肿瘤细胞代谢,从而使肿瘤的转移性、耐药性以及减瘤手术的可切除性发生改变。作者综合分析相关文献,对恶性腹水在卵巢癌发展过程中的形成机制,以及其与卵巢癌转移、耐药相关性的研究进展进行综述。

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