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性别相关因素对甲状腺癌发生发展的影响
作者:徐发展1  姜超喻2  伊丹丹2  史先彪2  王儒2  秦佳波1  桑剑锋1 
单位:1. 南京医科大学 鼓楼临床医学院, 江苏 南京 211166;
2. 南京鼓楼医院 普通外科, 江苏 南京 210008
关键词:甲状腺癌 性别差异 雌激素 生殖因素 综述 
分类号:R736.1
出版年·卷·期(页码):2023·42·第一期(154-159)
摘要:

甲状腺癌存在明显的性别差异,比如女性发病率更高,发病年龄更年轻,而男性就诊时所处的肿瘤阶段更晚,不过预后仍存在争议。性激素是产生该性别差异的重要因素,特别是雌激素对甲状腺癌的作用近年得到了较为广泛的研究。而妊娠等女性独有的生殖行为和性染色体这些具有明显性别差异的因素也可能影响甲状腺癌的发生发展。本文作者就性激素、生殖因素和遗传物质等性别相关因素与甲状腺癌发生发展关系的研究进展作一综述。

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