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缺氧诱导因子-1α与胰腺癌关系的研究进展
作者:刘义  徐克群  朱颖蔚 
单位:南京医科大学附属常州市第二人民医院 肿瘤科, 江苏 常州 213003
关键词:胰腺癌 缺氧诱导因子1α 分子机制 文献综述 
分类号:R735.9
出版年·卷·期(页码):2022·41·第二期(287-290)
摘要:

胰腺癌是常见的消化系统恶性肿瘤,其早期诊断率低且传统抗肿瘤治疗疗效有限,患者生存率极低。乏氧是影响胰腺癌生长、侵袭与转移的重要因素之一。而缺氧诱导因子1α(HIF-1α)在调节细胞内氧代谢的过程中发挥关键作用,作者就HIF-1α在胰腺癌发生机制中的最新研究进展进行综述,以期为临床治疗提供借鉴。

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