瑞芬太尼在肝癌切除术中的麻醉效果评价-东南大学学报医学版

瑞芬太尼在肝癌切除术中的麻醉效果评价

作者：谢燕

单位：东台市中医院麻醉科, 江苏东台 224200

分类号：R735.7;R971.2

出版年·卷·期（页码）：2022·41·第二期（265-268）

摘要：

目的:观察瑞芬太尼对肝癌切除术患者的麻醉效果及对患者Ramsay评分、视觉模拟评分法(VAS)评分的影响。方法:选取2017年1月至2021年7月在我院接受肝癌切除术的患者为研究对象,并根据麻醉药物的使用分为观察组(使用丙泊酚、瑞芬太尼)和对照组(使用丙泊酚、芬太尼)。观察比较两组患者术后认知功能以及Ramsay评分、VAS评分、苏醒质量的差异。结果:观察组患者术后1、3、5 h的认知功能得分高于对照组(P＜0.01),术后1、3、5 h的VAS得分低于对照组(P＜0.01),两组患者Ramsay得分差异无统计学意义(P＞0.05),两组患者呼吸恢复时间、指令恢复时间、睁眼时间、拔管时间以及尿潴留、低血压发生率差异均无统计学意义(均P＞0.05)。结论:瑞芬太尼对肝癌切除术患者具有较好的麻醉效果,对患者术后认知功能影响小。

Objective: To observe and analyze the anesthetic effect of remifentanil and its influence on Ramsay score and visual analogue scale(VAS) score in patients undergoing liver cancer resection. Methods: Patients undergoing liver cancer resection in our hospital from January 2017 to July 2021 were selected as our research subjects. The patients were divided into observation group(propfol combined with remifentanil) and control group(propofol combined with fentanyl) according to the use of different anesthetic drugs. The differences of postoperative cognition, Ramsay score and VAS score between the two groups were observed and compared. Results: The cognitive function scores at 1,3 and 5 hours after operation in the observation group were significantly higher than those in the control group(P＜0.01), while the VAS scores in the observation group were lower than those in the control group(P＜0.01). There was no statistically significant difference in Ramsay scores, respiratory recovery time, command recovery time, blink time, extubation time and the incidence of urinary retention and hypotension between the two groups(P＞0.05). Conclusion: Remifentanil has a good anesthetic effect on patients with liver cancer resection and little effect on postoperative cognitive function of the patients.

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