BONNER W M,REDON C E,DICKEY J S,et al.GammaH2AX and cancer[J].Nat Rev Cancer,2008,8(12):957-967.
 CHEN L S,FU L N,KONG X,et al.Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer[J].Br J Cancer,2014,110(4):1014-1026.
 GONG F,MILLER K M.Histone methylation and the DNA damage response[J].Mutat Res,2019,780:37-47.
 SHARMA A K,HENDZEL M J.The relationship between histone posttranslational modification and DNA damage signaling and repair[J].Int J Radiat Biol,2019,95(4):382-393.
 BARTKOVA J,HOR∨EJŠÍ Z,KOED K,et al.DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis[J].Nature,2005,434(7035):864-870.
 ITO T,TEO Y V,EVANS S A,et al.Regulation of cellular senescence by polycomb chromatin modifiers through distinct DNA damage and histone methylation-dependent pathyways[J].Cell Rep,2018,22(13):3480-3492.
 HAHM J Y,KIM J Y,PARK J W,et al.Methylation of UHRF1 by SET7 is essential for DNA double-strand break repair[J].Nucleic Acids Res,2019,47(1):184-196.
 SUN Y L,JIANG X F,XU Y,et al.Histone H3 methylation links DNA damage detection to activation of the tumor suppressor Tip60[J].Nat Cell Biol,2009,11(11):1376-1382.
 PAPPA S,PADILLA N,IACOBUCCI S,et al.PHF2 histone demethylase prevents DNA damage and genome instability by controlling cell cycle progression of neural progenitors[J].Proc Natl Acad Sci USA,2019,116(39):19464-19473.
 CASTELLINI L,MOON E J,RAZORENOVA O V,et al.KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage[J].Nucleic Acids Res,2017,45(7):3674-3692.
 JIANG Y H,QIAN X,SHEN J F,et al.Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation[J].Nat Cell Biol,2015,17(9):1158-1168.
 ZHENG H,CHEN L,PLEDGER W J,et al.p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression[J].Oncogene,2014,33(6):734-744.
 YUZUGULLU O G,CARMAN C,SERAFIM R B,et al.Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity[J].Oncotarget,2017,8(15):24518-24532.
 MAR B G,CHU S H,KAHN J D,et al.SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia[J].Blood,2017,130(24):2631-2641.
 PEI H D,ZHANG L,LUO K T,et al.MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites[J].Nature, 2011,470(7332):124-128.
 WYSOCKI R,JAVAHERI A,ALLARD S,et al.Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9[J].Mol Cell Biol,2005,25(19):8430-8443.
 HUYEN Y,ZGHEIB O,JR R A D,et al.Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks[J].Nature,2004,432(7015):406-411.
 KARI V,RAUL S K,HENCK J M,et al.The histone methyltransferase DOT1L is required for proper DNA damage response,DNA repair,and modulates chemotherapy responsiveness[J].Clin Epigenetics,2019,11(1):4.
 DUAN L,PEREZ R E,LAI X,et al.The histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells[J].J Biol Chem,2019,294(23):9186-9197.
 DUAN L,PEREZ R E,CHASTAIN P D,et al.JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells[J].Oncogene,2019,38(28):5643-5657.