Objective: To observe state of anxiety and depression of patients with common psychosomatic dermatosis in a dermatology clinic of a general hospital, explore the relationship between common psychosomatic dermatosis and emotions, and provide a basis for the psychotherapy of psychosomatic dermatosis. Methods: Patients in the dermatology clinic of a general hospital in Beijing were screened to record the general condition of the patient's general status, as well as the skin problems of the patient at the current week, and the state of anxiety and depression in patients was assessed by using Hospital Anxiety and Depression Scale (HADS), and which was compared with the domestic norm. Results: This study enrolled 646 dermatology outpatients, including 228 males and 418 females, aged (33.85±11.45) years. The HADS anxiety score was (5.19±3.05) points and the HADS depression score was (7.16±2.91) points, which were significantly higher than the domestic norm (P<0.05). A total of 108 patients with anxiety score>7 and depression score>7 included 57 patients with acne. 18 patients (30.51%) with chronic simple lichen had suspicious / significant anxiety status; 75 patients (53.57%) had hair loss suspicious / significant depression status. Conclusion: Patients with common psychosomatic dermatosis have significant anxiety and depression, and depression is more severe. Among them, the anxiety and depression co-morbidity state of acne patients are more common. The proportion of anxiety state is higher in patients with chronic simple lichen and the proportion of depression state is higher in patients with hair loss. For patients with refractory recurrent psychosomatic dermatosis, assessment can be performed and targeted psychotherapy is done.