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维拉帕米治疗丛集性头痛机制研究进展
作者:彭中兴1 2  王耀晨2  赵艳丽2  李公豪2  尹德录2  汤成春3  赵云峰2 
单位:1. 南京医科大学 康达学院, 江苏 连云港 222000;
2. 连云港市第一人民医院 心内科, 江苏 连云港 222000;
3. 东南大学附属中大医院 心内科, 江苏 南京 210009
关键词:维拉帕米 丛集性头痛 作用机制 综述 
分类号:R747.2
出版年·卷·期(页码):2020·39·第四期(538-542)
摘要:

丛集性头痛是一种剧烈的原发性头痛,具有周期性发作及昼夜节律的特点,急性期治疗措施包括高流量吸氧、曲坦类药物,同时行预防性治疗控制复发。维拉帕米是预防的首选药物,具体机制不明确,可能与作用于下丘脑及三叉神经血管系统、影响炎症肽类及NO等的释放有关。本文作者旨在综述维拉帕米用于预防丛集性头痛的可能作用机制。

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