超声造影在乳腺导管内乳头状瘤诊断中的应用分析-东南大学学报医学版

超声造影在乳腺导管内乳头状瘤诊断中的应用分析

单位：南京中医药大学附属医院, 江苏南京 210029

分类号：R737.9

出版年·卷·期（页码）：2020·39·第三期（301-305）

摘要：

目的:探讨超声造影对导管内乳头状瘤的诊断价值。方法:回顾性分析51例均经手术病理证实的导管内乳头状瘤患者的62个病灶彩色多普勒超声声像图及超声造影的特征。结果:乳腺导管内乳头状瘤的超声造影多表现为高增强、造影剂分布均匀、增强后形态规则、边缘清晰。61个(98.4%,61/62)病灶超声造影后呈高增强,46个(74.2%,46/62)病灶超声造影后有清晰的边缘,33个(53.2%,33/62)病灶造影后增强范围较二维超声图像范围无明显变化。乳腺导管内乳头状瘤病灶超声造影上升时间(rise time,RT)、峰值强度(peak intensity,PI)、曲线下面积(area under the curve,AUC)和达峰时间(time to peak,TTP)与周围腺体比较差异均有统计学意义(P<0.05)。结论:导管内乳头状瘤的彩色多普勒超声图像及超声造影表现有一定特异性,两者结合有助于提高其病灶的检出率及诊断准确性。

Objective:To explore the value of ultrasonography in the diagnosis of intraductal papilloma. Methods:Color Doppler sonography and contrast-enhanced ultrasonography of 62 lesions in 51 patients with intraductal papilloma confirmed by surgical pathology were retrospectively analyzed. Results:The contrast-enhanced ultrasonography of intraductal papilloma of the mammary gland was characterized by high enhancement, uniform distribution of contrast agents, regular morphology after enhancement, and clear edge. 61(98.4%,61/62) lesions showed high enhancement after sonography, 46(74.2%,46/62) lesions had clear edges after sonography, and 33(53.2%,33/62) lesions showed no significant change in the range of enhancement after sonography compared with the range of two-dimensional ultrasound images. The contrast-enhanced time (RT), peak intensity (PI), area under the curve (AUC), and peak time (TTP) of intraductal papilloma lesions of the mammary gland were statistically significant compared the peripheral glands (P<0.05). Conclusion:There is limited specificity in both two-dimensional ultrasound images and contrast-enhanced ultrasonography when diagnosing intraductal papilloma, however, the combination of the two methods can be quite helpful to improve the detection rate and diagnostic accuracy of the lesions.

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