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68Ga/177Lu-PSMA在淋巴结转移的高危前列腺癌诊疗一体化中的研究进展
作者:潘高健1  秦志强2  许露伟2  贾瑞鹏1 2 
单位:1. 东南大学 医学院, 江苏 南京 210009;
2. 南京医科大学附属南京医院 泌尿外科, 江苏 南京 210006
关键词:高危前列腺癌 68Ga/177Lu-前列腺特异性膜抗原 淋巴结转移 诊疗一体化 文献综述 
分类号:R737.25
出版年·卷·期(页码):2020·39·第二期(244-247)
摘要:

前列腺癌是严重危害全世界老年男性健康的恶性肿瘤。近年来我国前列腺癌的发病率迅速上升,已成为影响老年男性健康的主要泌尿系统恶性肿瘤。前列腺特异性膜抗原(PSMA)正电子发射计算机断层显像/计算机断层扫描(PET/CT)作为一种新型的诊疗手段,因其特异性的显像效果及病灶高浓聚优势,受到了泌尿外科临床医师的关注及追捧。采用诊断性核素68Ga标记的PSMA PET/CT对前列腺癌的早期诊断和预后评估起到积极的作用。此外,治疗性核素177Lu标记的PSMA PET/CT能够一定程度上抑制前列腺癌的生长,尤其适用于高危前列腺癌患者。作者综合上述研究,对68Ga-PSMA和177Lu-PSMA在淋巴结转移的高危前列腺癌诊疗一体化中的研究进展进行综述。

参考文献:

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