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醒后卒中的研究进展
作者:刘雪婷  张志珺 
单位:东南大学 医学院, 江苏 南京 210009
关键词:醒后卒中 缺血性脑卒中 静脉溶栓 机械取栓 文献综述 
分类号:R741
出版年·卷·期(页码):2019·38·第六期(1107-1111)
摘要:

醒后卒中(WUS)占缺血性脑卒中的9.7%~29.6%,但因其发病时间不明确、发病机制不清楚,故在预防和治疗上一直都是临床医师面临的难题。静脉溶栓和机械取栓被认为是现阶段急性缺血性脑卒中的一线治疗方案。为改善WUS的预后,大量临床研究对WUS的危险因素、溶栓筛选、取栓时间窗进行探索分析。作者就WUS的近期研究进展作一综述。

参考文献:

[1] AHMED N,WAHLGREN N,GROND M,et al.Implementation and outcome of thrombolysis with alteplase 3-4.5 h after an acute stroke:An updated analysis from sits-istr[J].Lancet Neurol,2010,9(9):866-874.
[2] WARDLAW J M,WARLOW C P,COUNSELL C.Systematic review of evidence on thrombolytic therapy for acute ischaemic stroke[J].Lancet,1997,350(9078):607-614.
[3] WANG Y L,LI Z X,ZHAO X Q,et al.Stroke care quality in china:Substantial improvement,and a huge challenge and opportunity[J].Int J Stroke,2017,12(3):229-235.
[4] SUN H,ZOU X,LIU L.Epidemiological factors of stroke:A survey of the current status in china[J].J Stroke,2013,15(2):109-114.
[5] MACKEY J.KLEINDORFER D.SUCHAREW H,et al.Population-based study of wake-up strokes[J].Neurology,2011,76(19):1662-1667.
[6] TANIMOTO A,MEHNDIRATTA P,KOO B B.Characteristics of wake-up stroke[J].J Stroke Cerebrovasc Dis,2014,23(6):1296-1299.
[7] BUCK D,SHAW L C,PRICE C I,et al.Reperfusion therapies for wake-up stroke:Systematic review[J].Stroke,2014,45(6):1869-1875.
[8] 张彭,毕国荣.醒后卒中的临床研究进展[J].辽宁医学杂志,2015,29(2):98-103.
[9] SUNG S M,LEE T H,CHO H J,et al.Clinical predictors for favorable outcomes from endovascular recanalization in wake-up stroke[J].J Clin Neurosci,2017,41:66-70.
[10] MORADIYA Y,JANJUA N.Presentation and outcomes of "wake-up strokes" in a large randomized stroke trial:Analysis of data from the international stroke trial[J].J Stroke Cerebrovasc Dis,2013,22(8):e286-292.
[11] RIMMELE D L,THOMALLA G.Wake-up stroke:Clinical characteristics,imaging findings,and treatment option-an update[J].Front Neurol,2014,5:35.
[12] ELLIOTT W J.Circadian variation in the timing of stroke onset-a meta-analysis[J].Stroke,1998,29(5):992-996.
[13] MARLER J R,PRICE T R,CLARK G L et al.Morning increase in onset of ischemic stroke[J].Stroke,1989,20(4):473-476.
[14] RICCIO P M,KLEIN F R,PAGANI CASSARÁ F,et al.Newly diagnosed atrial fibrillation linked to wake-up stroke and tia hypothetical implications[J].Neurology,2013,80(20):1834-1840.
[15] PATYAR S,PATYAR R R.Correlation between sleep duration and risk of stroke[J].J Stroke Cerebrovasc Dis,2015,24(5):905-911.
[16] KHEIRANDISH-GOZAL L,PHILBY M F,QIAO Z,et al.Endothelial dysfunction in children with obstructive sleep apnea is associated with elevated lipoprotein-associated phospholipase a2 plasma activity levels[J].J Am Heart Assoc,2017,6(2):e004923.
[17] HSIEH S W,LAI C L,LIU C K,et al.Obstructive sleep apnea linked to wake-up strokes[J].J Neurol,2012,259(7):1433-1439.
[18] MOHAMMAD Y,ALMUTLAQ A,AL-RUWAITA A,et al.Stroke during sleep and obstructive sleep apnea:There is a link[J].Neurol Sci,2019,40(5):1001-1005.
[19] CICCONE A,PROSERPIO P,ROCCATAGLIATA D V,et al.Wake-up stroke and tia due to paradoxical embolism during long obstructive sleep apnoeas:A cross-sectional study[J].Thorax,2013,68(1):97-104.
[20] HUISA B N,RAMAN R,ERNSTROM K,et al.Alberta stroke program early CT score (ASPECTS) in patients with wake-up stroke[J].J Stroke Cerebrovasc Dis,2010,19(6):475-479.
[21] ODLAND A,SAERVOLL P,ADVANI R,et al.Are the current MRI criteria using the DWI-FLAIR mismatch concept for selection of patients with wake-up stroke to thrombolysis excluding too many patients?[J].Scand J Trauma Resus,2015,23(22):1-6.
[22] THOMALLA G,SIMONSEN C Z,BOUTITIE F,et al.Mri-guided thrombolysis for stroke with unknown time of onset[J].N Engl J Med,2018,379(7):611-622.
[23] THOMALLA G,CHENG B,EBINGER M,et al.DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4.5 h of symptom onset (PRE-FLAIR):A multicentre observational study[J].Lancet Neurol,2011,10(11):978-986.
[24] WARDLAW J M,MURRAY V,BERGE E,et al.Recombinant tissue plasminogen activator for acute ischaemic stroke:An updated systematic review and meta-analysis[J].Lancet,2012,379(9834):2364-2372.
[25] HANKEY G J.Stroke[J].Lancet,2017,389(10069):641-654.
[26] THOMALLA G,FIEBACH J B,OSTERGAARD L,et al.A multicenter,randomized,double-blind,placebo-controlled trial to test efficacy and safety of magnetic resonance imaging-based thrombolysis in wake-up stroke (wake-up)[J].Int J Stroke,2014,9(6):829-836.
[27] ROVERI L,LA GIOIA S,GHIDINELLI C,et al.Wake-up stroke within 3 hours of symptom awareness:Imaging and clinical features compared to standard recombinant tissue plasminogen activator treated stroke[J].J Stroke Cerebrovasc Dis,2013,22(6):703-708.
[28] COSTA R,PINHO J,ALVES J N,et al.Wake-up stroke and stroke within the therapeutic window for thrombolysis have similar clinical severity,imaging characteristics,and outcome[J].J Stroke Cerebrovasc Dis,2016,25(3):511-514.
[29] SCHWAMM L H,WU O,SONG S S,et al.Intravenous thrombolysis in unwitnessed stroke onset:Mr witness trial results[J].Ann Neurol,2018,83(5):980-993.
[30] 胡玥,何欣威,刘译升,等.机械取栓在醒后卒中治疗中应用的研究进展[J].上海交通大学学报(医学版),2018,38(9):1129-1132.
[31] KUNTZE SÖDERQVIST Å,ANDERSSON T,WAHLGREN N,et al.Mechanical thrombectomy in acute ischemic stroke-patients with wake-up stroke and the elderly may benefit as well[J].J Stroke Cerebrovasc Dis,2016,25(9):2276-2283.
[32] ALBERS G W,LANSBERG M G,KEMP S,et al.A multicenter randomized controlled trial of endovascular therapy following imaging evaluation for ischemic stroke (defuse 3)[J].Int J Stroke,2017,12(8):896-905.
[33] NOGUEIRA R G,JADHAV A P,HAUSSEN D C,et al.Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct[J].N Engl J Med,2018,378(1):11-21.
[34] ESCALARD S,GORY B,KYHENG M,et al.Unknown-onset strokes with anterior circulation occlusion treated by thrombectomy after dwi-flair mismatch selection[J].EUR J Neurol,2018,25(5):732-738.
[35] BHASKAR S,STANWELL P,CORDATO D,et al.Reperfusion therapy in acute ischemic stroke:Dawn of a new era?[J].BMC Neurology,2018,18(1):8.

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