Objective: To compare the effects of three kinds of anesthesia induction schemes for gynecological laparoscopic surgery. Methods: One hundred and twenty patients underwent gynecological laparoscopic surgery were randomly divided into sufentanil group (S group), oxycodone group (Q group) and oxycodone combined with transverse abdominal muscle block group (Q-TAP group), each group containing 40 patients. General anesthesia was induced by sufentanil and oxycodone respectively. In the Q-TAP group, bilateral TAP block was conducted under B-ultrasound guidance after intubation(0.375% ropivacaine 20 ml was injected into each side). The changes of heart rate (HR) and systolic blood pressure of the patients during intubation, intraoperative and postoperative opioids consumption, extubation time, postanesthesia care unit (PACU) stay time, visual analogue scale (VAS) pain score of the patients 30 min after extubation, 2, 4, 8 and 24 hours after surgery, and the occurrence of anaesthesia related complications (nausea, vomiting, dizziness, drowsiness, respiratory inhibition) were observed and recorded. Results: The intraoperative remifentanil consumption and postoperative VAS pain score of Q-TAP group were significantly lower than those of Q group and S group (all P < 0.05). The fluctuations of HR during intubation were smaller and the frequency of analgesic relief in PACU was lower in Q group and Q-TAP group than those in S group (P < 0.05). There were no statistical difference in extubation time, PACU stay time, and postoperative complications among the three groups. Conclusion: Compared with sufentanil, general anesthesia induced with oxycodone can reduce the HR fluctuation during intubation. General anesthesia induced with oxycodone combined with TAP block for gynecological laparoscopic surgery can reduce intraoperative and early postoperative opioid consumption, and improve postoperative analgesia, without complication increase. |
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