目的：分析补佳乐联合芬吗通及阿司匹林对宫腔镜下冷刀（HEOS冷刀）分离宫腔粘连（IUA）术后月经恢复情况、美国生育协会宫腔粘连评分（AFS评分）及生育率改善情况，为临床给药方式提供一个新的参考。方法：选取2016年1月至2017年12月在东南大学附属中大医院就诊的中-重度IUA患者66例，平均分为两组，实验组HEOS冷刀术后给予补佳乐联合芬吗通及阿司匹林治疗，对照组给予补佳乐联合地屈孕酮治疗。结果：与术前相比，两种给药方式均可明显降低术后的AFS评分，其中实验组降低更明显，且可减少术后复查的次数，差异有统计学意义（P<0.05）；术后的月经改善方面两组无明显差异（P>0.05）；实验组与对照组比较有更高的术后生育率，差异有统计学意义（P<0.05）。结论：HEOS冷刀分离IUA术后应用补佳乐联合芬吗通及阿司匹林口服治疗，可以有效增加月经量，降低术后AFS评分，减少平均复查次数，提高术后妊娠率。

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