Objective: To analyze the risk factors of Wanger classification and antibiotic defined daily doses(DDDs) in hospitalized diabetic foot patients. Methods: 429 patients with diabetic foot in Zhongda Hospital Affiliated to Southeast University from July 2013 to September 2016 were selected as the subjects. The basic information of age, biochemical index, antibiotic utilization, pathogen culture and multidrug resistance, complication, diabetic foot, and prognosis of ulcer at discharge were collected by retrospective analysis. Multiple linear regression and ordered Logistic regression were used to analyze the data. Results: According to inclusion and exclusion criteria, 280 eligible cases were finally included. Ordered Logistic regression analysis showed that age (P<0.01), serum albumin (P<0.01), duration of diabetes mellitus (P<0.05) and hemodynamic assessment of both lower limbs (P<0.01) were risk factors for diabetic foot classification;multiple linear regression analysis showed that age (P<0.01), kidney disease (P<0.05) and serum albumin (P<0.01) were the related risk factors of DDDs of antibiotics. Conclusion: Young age, low serum albumin level, long course of diabetes, and poor hemodynamic assessment of both lower extremities are risk factors for deteriorated foot disease. Diabetic foot patients with young age, low serum albumin level and no kidney disease tend to have greater intensity of antibiotic use.
 JIANG Y,WANG X,XIA L,et al.A cohort study of diabetic patients and diabetic foot ulceration patients in China[J].Wound Repair Regen,2015,23(2):222-230.
 JIANG Y,RAN X,JIA L,et al. Epidemiology of type 2 diabetic foot problems and predictive factors for amputation in China[J].Int J Low Extrem Wounds,2015,14(1):19-27.
 DATTA P,CHANDER J,GUPTA V,et al.Evaluation of various risk factors associated with multidrug-resistant organisms isolated from diabetic foot ulcer patients[J].J Lab Physicians,2019,11(1):58-62.