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miRNA与血管性痴呆的研究进展
作者:詹莹1  安红伟2 
单位:1. 广西中医药大学, 广西 南宁 530001;
2. 柳州市中医院 神经内科, 广西 柳州 545001
关键词:miRNA 血管性痴呆 综述 
分类号:R741
出版年·卷·期(页码):2019·38·第二期(376-379)
摘要:

血管性痴呆(VaD)是以缺血缺氧性或出血性脑损伤造成的以智能、认知功能障碍为主的临床综合征。近年来,VaD发病率逐年增加,严重影响人类的生活质量。MicroRNA (miRNA)在生物体的生长、发育以及疾病的发生、发展等过程中都起着非常重要的作用。越来越多的研究表明miRNA与VaD有关,miRNA可能通过刺激神经元死亡及炎症的发生促进细胞凋亡及氧化应激,对生物体的学习记忆功能产生影响。作者将就miRNA与VaD的研究进展作一综述。

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