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CT与MR造影对小肠克罗恩病诊断价值比较的Meta分析
作者:徐孝新  陈洪 
单位:东南大学附属中大医院 消化科, 江苏 南京 210009
关键词:克罗恩病 计算机断层扫描造影 磁共振造影 Meta分析 
分类号:R445.2;R814.42;R574.5
出版年·卷·期(页码):2019·38·第二期(223-229)
摘要:

目的:采用Meta分析比较计算机断层扫描成像技术(CTE)与磁共振成像(MRE)对小肠克罗恩病(CD)的诊断价值。方法:检索数据库并收集关于CTE及MRE诊断小肠CD的文献,进行统计分析得到CTE及MRE两组诊断试验的合并敏感度、特异度、诊断比值比(DOR)及受试者工作特征曲线的曲线下面积(AUC),比较两者对小肠CD的诊断效能以及活动性和并发症的检测能力。结果:CTE组合并敏感度、特异度和DOR分别为81%、82%和16.67,而MRE组分别为88%、90%和40.58,两组的AUC分别为0.8728和0.894 5。采用Z检验比较两组的诊断效能,差异无统计学意义(Z=1.65,P>0.05)。且CTE与MRE对CD并发症(如狭窄、瘘管、脓肿等)及活动性的检测能力差异无统计学意义。结论:CTE与MRE对于CD具有良好的、相似的诊断能力,同时对活动性及并发症的检测能力无显著区别。

Objective:To compare the diagnostic value of computed tomography enterography (CTE) and magnetic resonance enterography(MRE) for small bowel Crohn disease (CD)by Meta-analysis. Methods:The databases were systematically searched for relevant articles on the diagnosis of CD using CTE or MRE. Data were pooled to yield summary sensitivity, specificity and the area under the SROC curve (AUC).Then they were compared in the diagnostic efficacy and the detectability of activity and complications. Results:The pooled sensitivity,specificity,DOR of CTE and MRE was 81%,82%,16.67 and 88%,90%,40.58.The AUC of CTE and MRE was 0.8728 and 0.894 5.The results of Z-test revealed there were no significant differences in diagnostic performance between CTE and MRE.There was no statistically significant difference between CTE and MRE in detecting CD complications(such as stenosis,abscess and fistula)and activity. Conclusion:CTE and MRE have high and similar performance in diagnosis of CD,and there is no significant difference in the detection abilities of activity and complications.

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