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宫颈癌预后生物学指标新进展
作者:丁岳  周怀君 
单位:南京大学医学院附属鼓楼医院 妇科, 江苏 南京 210093
关键词:宫颈癌 预后 生物学指标 
分类号:R737.33
出版年·卷·期(页码):2019·38·第一期(192-195)
摘要:

宫颈癌是全世界女性最常见的恶性肿瘤之一,其发病率和死亡率与经济水平相关。由于对患者的预后判断及治疗方式的选择仍依靠TNM分期等组织病理学分期方式,易受医生主观因素影响,对宫颈癌的预后判断有一定偏差,造成医疗资源浪费且不利于治疗的开展。引入客观生物学指标,有助于提高预后判断的准确性。

参考文献:

[1] SATHYANARAYANAN A,CHANDRASEKARAN K S,KARUNAGARAN D.microRNA-145 modulates epithelial-mesenchymal transition and suppresses proliferation,migration and invasion by targeting SIP1 in human cervical cancer cells[J].Cell Oncol (Dordr),2017,40(2):119-131.
[2] COLEMAN M P.Cancer survival:global surveillance will stimulate health policy and improve equity[J].Lancet,2014,383(9916):564-573.
[3] 陈慧,周思园,孙振球.常见妇科三大恶性肿瘤的流行及疾病负担研究现状[J].中国现代医学杂志,2015,25(6):108-112.
[4] 王彤,吴玉梅.宫颈癌分期的历史回顾、面临的问题与未来发展[J].中国医药导报,2017,14(24):46-49.
[5] TANG H,WANG Y,ZHANG B,et al.High brain acid soluble protein 1(BASP1) is a poor prognostic factor for cervical cancer and promotes tumor growth[J].Cancer Cell Int,2017,17:97.
[6] LIU H Q,WANG Y H,WANG L L,et al.P16INK4A and survivin:Diagnostic and prognostic markers in cervical intraepithelial neoplasia and cervical squamous cell carcinoma[J].Exp Mol Pathol,2015,99(1):44-49.
[7] WANG B,HUANG Z,GAO R,et al.Expression of long noncoding RNA urothelial cancer associated 1 promotes cisplatin resistance in cervical cancer[J].Cancer Biother Radiopharm,2017,32(3):101-110.
[8] PALIOURAS A R,MONTEVERDE T,GAROFALO M.Oncogene-induced regulation of microRNA expression:Implications for cancer initiation,progression and therapy[J].Cancer Lett,2018,241:152-160.
[9] HE S,LIAO B,DENG Y,et al.MiR-216b inhibits cell proliferation by targeting FOXM1 in cervical cancer cells and is associated with better prognosis[J].BMC Cancer,2017,17(1):673.
[10] ZENG F,XUE M,XIAO T,et al.MiR-200b promotes the cell proliferation and metastasis of cervical cancer by inhibiting FOXG1[J].Biomed Pharmacother,2016,79:294-301.
[11] LIU T Y,CHEN J,SHANG C L,et al.Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer[J].J Exp Clin Cancer Res,2016,35(1):170.
[12] EOH K J,PAEK J,KIM S W,et al.Long non-coding RNA,steroid receptor RNA activator (SRA),induces tumor proliferation and invasion through the NOTCH pathway in cervical cancer cell lines[J].Oncol Rep,2017,38(6):3481-3488.
[13] WANG J,OU J,GUO Y,et al.TBLR1 is a novel prognostic marker and promotes epithelial-mesenchymal transition in cervical cancer[J].Br J Cancer,2014,111(1):112-124.
[14] HOU T,TONG C,KAZOBINKA G,et al.Expression of COL6A1 predicts prognosis in cervical cancer patients[J].Am J Transl Res,2016,8(6):2838-2844.
[15] TANAKA T,TERAI Y,KOGATA Y,et al.CD24 expression as a marker for predicting clinical outcome and invasive activity in uterine cervical cancer[J].Oncol Rep,2015,34(5):2282-2288.
[16] TANG J,YANG Z,WANG Z,et al.Foxp3 is correlated with VEGF-C expression and lymphangiogenesis in cervical cancer[J].World J Surg Oncol,2017,15(1):173.
[17] ZOU D,ZHOU Q,WANG D,et al.The Downregulation of MicroRNA-10b and its Role in Cervical Cancer[J].Oncol Res,2016,24(2):99-108.
[18] SATHYANARAYANAN A,CHANDRASEKARAN K S,KARUNAGARAN D.microRNA-146a inhibits proliferation,migration and invasion of human cervical and colorectal cancer cells[J].Biochem Biophys Res Commun,2016,480(4):528-533.
[19] FANG H,SHUANG D,YI Z,et al.Up-regulated microRNA-155 expression is associated with poor prognosis in cervical cancer patients[J].Biomed Pharmacother,2016,83:64-69.
[20] JIANG W,PAN J J,DENG Y H,et al.Down-regulated serum microRNA-101 is associated with aggressive progression and poor prognosis of cervical cancer[J].J Gynecol Oncol,2017,28(6):e75.
[21] WEI W F,ZHOU C F,WU X G,et al.MicroRNA-221-3p,a TWIST2 target,promotes cervical cancer metastasis by directly targeting THBS2[J].Cell Death Dis,2017,8(12):3220.
[22] SUN L,JIANG R,LI J,et al.MicoRNA-425-5p is a potential prognostic biomarker for cervical cancer[J].Ann Clin Biochem,2017,54(1):127-133.
[23] LIN J,LU J,WANG C,et al.The prognostic values of the expression of Vimentin,TP53,and Podoplanin in patients with cervical cancer[J].Cancer Cell Int,2017,17(1):80-92.
[24] BEYER S,ZHU J,MAYR D,et al.Histone H3 acetyl K9 and histone H3 Tri methyl K4 as prognostic markers for patients with cervical cancer[J].Int J Mol Sci,2017,18(3):477-491.
[25] YANG P,CHEN N,YANG D,et al.The ratio of serum angiopoietin-1 to angiopoietin-2 in patients with cervical cancer is a valuable diagnostic and prognostic biomarker[J].PeerJ,2017,5(6):e3387.
[26] FRIESE K,KOST B,VATTAI A,et al.The G protein-coupled estrogen receptor (GPER/GPR30) may serve as a prognostic marker in early-stage cervical cancer[J].J Cancer Res Clin Oncol,2017,144(1):13-19.
[27] REFAAT T,DONNELLY E D,SACHDEV S,et al.c-Met Overexpression in cervical cancer,a prognostic factor and a potential molecular therapeutic target[J].Am J Clin Oncol,2015,93(3):E252.
[28] KIM B W,CHO H,CHUNG J Y,et al.Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry[J].J Transl Med,2013,11:185.
[29] SUN B,YE X F,LI Y,et al.Lgr5 is a potential prognostic marker in patients with cervical carcinoma[J].Int J Clin Exp Patho,2015,8(2):1783-1789.
[30] CHO H,CHUNG J Y,KIM S,et al.MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer[J].BMC Cancer,2014,14(1):957.
[31] HEEREN A M,PUNT S,BLEEKER M C,et al.Prognostic effect of different PD-L1 expression patterns in squamous cell carcinoma and adenocarcinoma of the cervix[J].Mod Pathol,2016,29(7):753-763.
[32] GARIMA,PANDEY S,PANDEY L K,et al.The role of p53 gene in cervical carcinogenesis[J].J Obstet Gynaecol India,2016,66(Suppl 1):383-388.
[33] CHENG L,WU S,ZHANG K,et al.A comprehensive overview of exosomes in ovarian cancer:emerging biomarkers and therapeutic strategies[J].J Ovarian Res,2017,10(1):73.
[34] PLEBANEK M P,ANGELONI N L,VINOKOUR E,et al.Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche[J].Nat Commun,2017,8(1):1319.

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