合理用药干预对外科预防性使用质子泵抑制剂的影响-东南大学学报医学版

合理用药干预对外科预防性使用质子泵抑制剂的影响

单位：东南大学附属中大医院药学部, 江苏南京 210009

分类号：R95

出版年·卷·期（页码）：2019·38·第一期（43-46）

摘要：

目的：比较干预前后外科质子泵抑制剂（PPIs）的预防使用情况。方法：回顾性分析干预前（2016年4-6月）我院泌尿外科手术病例513例和同期干预后（2017年4-6月）手术病例623例，比较PPIs的预防使用情况。结果：干预前后PPIs预防使用率分别为80.51%和74.48%，两组比较有统计学差异（P<0.05）；干预前后PPIs合理使用率分别为21.64%和28.41%，两组比较差异有统计学意义（P<0.01）。结论：对外科PPIs预防应用的药学干预措施可行且有效，促进了PPIs的合理使用。

Objective:To Compare the use of proton pump inhibitors before and after intervention in surgical department. Methods:This retrospective study assessed 513 patients before intervention(2016.4-6)and 623 patients after intervention(2017.4-6)in urology department to compare the usage of PPIs.Results:The treatment rate before and after intervention of PPIs was 80.51% and 74.48%, respectively.The differences were statistically significant(P<0.05).The reasonable use rate before and after intervention of PPIs was 21.64% and 28.41%, respectively.There were significantly statistical differences in comparison of data between the two groups(P<0.01).Conclusions:The pharmacy interventions for the preventire use of PPIs in Surgical Department are feasible and effective, thus the rational use of PPIs is promoted.

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