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经脐静脉中心静脉置管在早产低出生体重儿中的临床应用
作者:夏晓芹  卢庆晖  彭爱霞  许瑶  张家杰  张松青 
单位:中山大学附属东华医院 新生儿科, 广东 东莞 523110
关键词:早产 低出生体重 脐静脉 中心静脉 外周静脉 置管 
分类号:R722.6
出版年·卷·期(页码):2018·37·第六期(1045-1048)
摘要:

目的:探讨经脐静脉中心静脉置管在早产低出生体重儿中的应用。方法:对133例早产低出生体重儿行经脐静脉中心静脉置管术(脐静脉组),观察置管后出口部位渗血渗液率、导管病原菌定植率、出口部位感染率及并发症的发生率,并与同期83例经外周中心静脉置管(外周静脉组)的早产低出生体重儿进行比较。结果:(1)中心静脉置管成功率脐静脉组为72.18%,外周静脉组为72.29%,两组差异无统计学意义(P=0.99)。(2)出口部位渗血渗液率、导管病原菌定植率及出口部位感染率脐静脉组分别为50.00%、14.91%及0,外周静脉组分别为20.48%、1.64%及12.05%,两组差异有统计学意义(分别P=0、0.01及0);非计划拔管率、导管相关血行感染率、胆汁淤积及坏死性小肠结肠炎发生率,脐静脉组分别为20.00%、6.15%、6.15%及2.31%;外周静脉组分别为14.81%、6.02%、6.02%及3.28%;两组差异无统计学意义(分别P=0.34、1.00、1.00及0.94)。(3)脐静脉组置管患儿年龄和留置时间分别为(12.76±9.12)h和(12.20±6.32)d;外周静脉组置管患儿年龄和留置时间分别为(11.18±6.11)h和(22.58±13.57)d。结论:经脐静脉中心静脉置管成功率与外周中心静脉置管相近,但脐静脉中心静脉置管操作方便,更利于早产低出生体重儿中早期应用。

Objective:To explore the clinical application of umbilical vein central venous catheter in the treatment of preterm infants with low birth weight. Methods:One hundred and thirty-three cases of catheter through umbilical vein center were selected as umbilical vein group, and 83 cases of infants who underwent peripherally inserted central venous catheter were regarded as peripheral vein group. The rates of catheter and complication of the two groups were observed. Results:(1) The central venous catheter placement success rate was 72.18% in the umbilical vein group and 72.29% in the peripheral vein group, there was no statistically significant difference between the two groups (P=0.99).(2) The exudation rate, bacterial colonization rate, exit site infection rate were 50.00%, 14.91% and 0 in umbilical vein group respectively and 20.48%, 1.64%, 12.05% in peripheral vein group respectively, there was no statistically significant difference between the two groups (P=0, 0.01, 0).The rate of unplanned intubation, catheter-related blood stream infection, the cholestasis and necrotizing enteritis were 20.00%, 6.15%, 6.15%, 2.31% in umbilical vein group respectively and 14.81%, 6.02%, 6.02%, 3.28% in peripheral vein group respectively, there were no significant difference between the two groups (P=0.34, 1.00, 1.00, 0.94).(3) The age and duration of indwelling catheter in umbilical vein group were (12.76±9.12) h, (12.20±6.32) d respectively and (11.18±6.11) h, (22.58±13.57) d in the peripheral vein group respectively. Conclusion:The success rate is similar between umbilical vein central venous catheterization and peripherally inserted central catheterization. However, umbilical vein central venous catheterization is easy to operate and it is more beneficial to premature birth weight infants in early stage.

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