MAJEED A,HWANG H G,CONNOLLY S J,et al.Management and outcomes of major bleeding during treatment with dabigatran or warfarin[J].Circulation,2013,128(21):2325-2332.
 RUFF C T,GIUGLIANO R P,BRAUNWALD E,et al.Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation:a meta-analysis of randomised trials[J].Lancet,2014,383(9921):955-962.
 BLACKSHEAR J L,ODELL J A.Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation[J].Ann Thorac Surg,1996,61(2):755-759.
 REDDY V Y,DOSHI S K,KAR S,et al.5-year after left atrial appendage closure:from the PREVAIL and PROTECT AF trials[J].J Am Coll Cardiol,2017,70(24):2964-2975.
 BOERSMA L V,INCE H,KISCHE S,et al.Efficacy and safety of left atrial appendage closure with WATCHMAN in patients with or without contraindication to oral anticoagulation:1-year follow-up outcome data of the EWOLUTION trial[J].Heart Rhythm,2017,14(9):1302-1308.
 DING J,ZHU J,LU J,et al.Transcatheter closure of the left atrial appendage:initial experience with the WATCHMAN device[J].Int J Clin Exp Med,2015,8(9):15230-15237.