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高频超声检测2型糖尿病患者下肢周围神经病变的临床价值
作者:张帆1  李慧1  雷威1  刘春节1  宋华勇2  侯晓东1 
单位:1. 河南大学第一附属医院 超声科, 河南 开封 475001;
2. 河南大学第一附属医院 肿瘤科, 河南 开封 475001
关键词:高频超声 2型糖尿病 周围神经病变 
分类号:R445.1;R587.1
出版年·卷·期(页码):2018·37·第四期(583-587)
摘要:

目的:探讨高频超声检测2型糖尿病(T2DM)以及并发周围神经病变(DPN)患者下肢主要神经的异常改变及其临床价值。方法:将64例T2DM患者分为T2DM并发DPN组(A组,32例)和T2DM不并发DPN组(B组,32例),另选取32例健康人为健康对照组(C组)。应用高频超声观察测量A、B及C组股神经和隐神经的宽、厚径及横截面积。结果:C组左、右侧股神经和隐神经宽、厚径及横截面积与身高、体质量呈正相关,差异有统计学意义(均P < 0.05)。与A组相比,B组和C组受试者的股神经和隐神经宽、厚径明显长及横截面积明显大,差异有统计学意义(均P < 0.05);与B组相比较,C组的宽、厚径明显长及横截面积明显大,差异有统计学意义(均P < 0.05)。结论:高频超声可检测2型糖尿病患者股神经和隐神经的异常改变,具有重要临床应用价值。

Objective:To explore abnormal changes and clinical value of high frequency ultrasonography(hf) in patients with diabetes mellitus(T2DM) and peripheral neuropathy(DPN). Method:Sixty four cases of T2DM were divided into:group A(T2DM with DPN group); Group B(T2DM without DPN group), 32 in each group. Another 32 healthy controls were selected for group C. In the three groups, the internal chorus and the structure of the nerve and the implicit nerve were observed, and the long diameter(D1), wide diameter(D2) and cross-sectional area(CSA) of the three groups of nerves were measured and compared. Results:The width, thickness and cross-sectional area of left and right femoral nerve and saphenous nerve in the healthy control group were positively correlated with height and weight(P<0.05). Compared with group A and group C, the width, thickness and cross-sectional area of saphenous nerve in group B and C increased significantly (P<0.05), and the width, thickness and cross-sectional area of group C were significantly larger than those of group B. The difference was statistically significant(P<0.05). The results showed that the width, thickness and cross-sectional area of T2DM patients decreased significantly, while the width, thickness diameter and cross-sectional area of T2DM combined with DPN group were the smallest, and the difference was statistically significant(P<0.05). Conclusion:High frequency ultrasound can display abnormal changes of type 2 diabetes mellitus and combined with femoral nerve and saphenous nerve abnormalities, which has important clinical application value.

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