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改良TLIF结合个性减压术与PLIF术治疗腰椎管狭窄症合并腰椎不稳的疗效比较
作者:汪小军  秦入结  任春朋  孙鹏浩  李垠 
单位:徐州医科大学 附属连云港医院, 江苏 连云港 222000
关键词:腰椎管狭窄症 腰椎不稳 脊柱融合术 椎板开窗减压 
分类号:R681.5
出版年·卷·期(页码):2018·37·第三期(496-501)
摘要:

目的:比较改良经椎间孔入路椎体间融合术(TLIF)结合个性减压术与经腰椎后路椎体间融合术(PLIF)治疗腰椎管狭窄症合并腰椎不稳的近期疗效。方法:回顾性分析我院应用手术治疗的93例腰椎管狭窄症合并腰椎不稳患者的资料,分为改良TLIF组47例和PLIF组46例,比较两组手术时间、术中出血量、视觉疼痛模拟评分(VAS)、日本骨科协会(JOA)评分、植骨融合效果及手术并发症发生率。结果:改良TLIF组手术时间、术中出血量均低于PLIF组(P<0.05);两组患者术后各随访点腰腿痛VAS、JOA评分较术前均明显改善(P<0.05),术后3、6个月时组间比较差异无统计学意义(均P>0.05),但PILF组术后1个月时腰痛VAS高于改良TLIF组(P<0.05);两组间融合率差异无统计学意义(P>0.05);改良TLIF组并发症发生率为8.51%,显著低于PILF组的23.91%(P<0.05)。改良TLIF组出现3例神经根损伤、1例脑脊液漏,PLIF组出现4例神经根损伤、2例脑脊液漏、1例硬脊膜撕裂、1例急性尿潴留、3例腰背肌乏力。结论:改良TLIF并个性化有限减压用于治疗腰椎管狭窄症合并腰椎不稳的疗效与PLIF相当,但对组织结构破坏少、内环境干扰小,手术并发症少,符合精准减压与微创理念。

Objective: To compare the short-term effects of modified transforaminal lumbar interbody fusion with limited decompression and posterior lumbar interbody fusion in the treatment of lumbar spinal stenosis with instability.Methods: 93 cases of lumbar spinal stenosis with instability were analyzed retrospectively. They were divided into two groups,including 47 cases underwent modified TLIF and 46 cases underwent PILF.The operaion time,average blood loss, the visual analogue score(VAS), the Japanese orthopedic association(JOA) score, incidence of complications and the effect of fusion were compared between the two groups.Results: The operaion time and average blood loss of modified TLIF group were significantly lower than those in the PLIF group(P<0.05). The VAS of low back and leg pain and the JOA score were improved in the two groups compared with preoperation at each follow up(P<0.05). There were no significant differences in VAS of low back and leg pain between the two groups at three months postoperation or six months postoperation(P>0.05), but the VAS of low back pain was lower in the modified TLIF group than that in the PLIF group at one month postoperatively(P<0.05). No statistical significance existed in the postoperative fusion rate at the latest follow up between the two groups(P>0.05). The incidence of complications in the modified TLIF group was 8.51%, while the PILF group was 23.91%. The incidence of complications in the modified TLIF group was significantly lower than that of the PILF group(P<0.05). There were three cases with nerve root injury,and one cases with cerebrospinal fluid leakage in the modified TLIF group, while four cases with nerve root injury, two cases with cerebrospinal fluid leakage, one case with dural tear, three cases of lumbar back muscle with fatigue and one case with acute urine retention.Conclusion: The modified TLIF with personalized decompression gets the satisfied effect just as PLIF in the treatment of lumbar spinal stenosis with instability. But it has less damage, less internal environment interference, fewer postoperative complications and it accords with the concept of precise decompression and minimally invasive surgery.

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