Objective: To study the ultrasound elastography in combination with TSH testing differential value to the diagnosis of patients with benign and malignant thyroid nodules and analyzed.Methods: From January 2015 to January 2017, our hospital was confirmed by pathological diagnosis of benign and malignant thyroid nodules in patients with thyroid nodule, 51 cases were respectively the ultrasound elasticity imaging in all patients, and serum TSH test. The individual diagnosis and the testing results were analyzed and the pathological results were compared.Results: Serum TSH level in patients with malignant nodules group for (6.2±0.2) mIU·L-1, higher than that of benign nodules group (2.6±0.2) mIU·L-1, with a significant difference (P<0.05). 54.90% (28/51) patients with benign nodule showed ultrasound elasticity imaging score of 1, was higher than that of malignant nodules of 0.00% (0/51), 9.80% (5/51) of the patients were rated a score of 3 which was lower than that of the control group 92.16%(47/51), all had significant differences (all P<0.05).Joint diagnosis basied on testing results of pathology. True positive rate and negative rate was 94.12% (48/51), 96.08% (49/51)higher than TSH diagnosis and ultrasound elasticity imaging diagnosis, with significant differences (all P<0.05).Joint TSH ultrasound elasticity imaging in the diagnosis of benign and malignant thyroid nodules of the sensitivity, specificity and accuracy were 94.12%, 96.08% and 95.10% respectively, and were higher than TSH diagnosis and ultrasound elasticity imaging diagnosis, had significant differences (all P<0.05).Conclusion: Ultrasound elastography in combination with TSH test in the diagnosis of benign and malignant thyroid nodules has a very good sensitivity, specificity and accuracy, worthy of clinical popularization and application. |
[1] AYUBI E,SAFIRI S.Lateral lymph node recurrence after total thyroidectomy and central neck dissection in patients with papillary thyroid cancer without clinical evidence of lateral neck metastasis:Comment on data sparsity[J].Oral Oncol,2017,8375(17):30086-30087.
[2] 张梅玉,李农,郭玲,等.高分辨率超声和超声弹性成像在甲状腺结节良恶性病变鉴别诊断中的对比研究[J].中国临床实用医学,2016,7(2):18-22.
[3] 廖飞鹏.实时超声弹性成像在甲状腺结节诊断中的应用价值[J].世界临床医学,2017,11(6):223-225.
[4] 刘震,马德寿,赵桂萍,等.甲状腺微小癌(TMC)进行超声弹性成像检查的诊断价值[J].医学信息,2017,30(5):256-257.
[5] 张燕,韩姣静.小金丸对甲状腺功能正常甲状腺结节患者血清TSH水平及临床疗效研究[J].中国生化药物杂志,2016,36(3):125-126.
[6] 姚丽.常规超声与超声弹性成像联合评分诊断甲状腺良恶性占位的效果[J].临床医学研究与实践,2017,2(3):130-132.
[7] CHENG L, JIN Y, LIU M,et al.HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancerharboring BRAFV600E[J].Oncotarget,2017,8(12):19843-19854.
[8] 刘馨,吴艺捷.超声压迫性弹性成像在良恶性甲状腺结节鉴别中的应用[J].中华普通外科学文献:电子版,2016,10(3):223-226.
[9] 李梅,陈宏,杨茹怡,等.超声新技术在甲状腺良恶性结节鉴别诊断中的应用[J].中国医学计算机成像杂志,2016,22(6):583-587.
[10] 马力,郭云怀,周苏晋,等.超声引导下细针穿刺活检和超声联合弹性成像诊断甲状腺结节的临床价值研究[J].中国医学创新,2016,13(36):86-88.
[11] 黄旴宁,符少清,吴煌福,等.常规超声与弹性成像在桥本甲状腺炎合并甲状腺微小癌中的应用价值[J].中国老年学杂志,2016,36(23):5956-5958.
[12] 于风霞,王建红,王彦华,等.弹性成像评分联合超声造影鉴别桥本甲状腺炎背景下结节良恶性临床价值的研究[J].中华内分泌代谢杂志,2016,32(4):307-308.
[13] 林玉晶,肖文华,洪天配,等.甲状腺结节中预测甲状腺乳头状癌的多因素分析:甲状腺球蛋白抗体的意义[J].中国微创外科杂志,2017,17(2):126-130.
[14] 董勇,贺建业,侯迎晨,等.甲状腺乳头状癌与结节性甲状腺肿患者甲状腺功能相关因素对比分析[J].中国医药,2017,12(1):68-71.
[15] 陈丽霞,彭玲,马先福,等.糖脂类代谢指标、血清TSH及尿碘对甲状腺癌发生风险的评估作用[J].中国医师杂志,2017,19(2):281-283.
[16] 刘佳,付鹏,杨志杰,等.促甲状腺激素受体mRNA联合99mTc-MIBI显像诊断甲状腺结节良恶性的价值[J].肿瘤学杂志,2016,22(5):384-388.
[17] 何远明.高频超声及弹性成像对甲状腺微小结节病变中的诊断价值[J].医学影像学杂志,2017,27(2):224-226.
[18] 舒凯,纪园园,张玉良,等.Q-analysis实时组织弹性成像定量分析在甲状腺实性结节良恶性鉴别中的应用[J].浙江临床医学,2017,19(2):331-332.
[19] 商宁,杜辉,李军,等.超声造影联合弹性成像在TI-RADS 4类甲状腺结节良恶性鉴别诊断中的应用价值研究[J].中国医学装备,2017,14(1):74-78.
[20] 何云霞.超声弹性成像与常规超声检查甲状腺结节的临床价值分析[J].中国现代药物应用,2017,11(4):48-50. |