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超声弹性成像联合TSH检测对甲状腺结节良恶性鉴别诊断的价值分析
作者:徐丹凤1  王志利2  刘洋1  祝小英1  杨漪1 
单位:1. 哈励逊国际和平医院 超声科, 河北 衡水 053000;
2. 哈励逊国际和平医院 核磁共振室, 河北 衡水 053000
关键词:甲状腺结节 血清促甲状腺激素 超声弹性成像 诊断价值 
分类号:R736.1;R445.1
出版年·卷·期(页码):2018·37·第一期(50-54)
摘要:

目的:研究超声弹性成像联合TSH检测对良恶性甲状腺结节患者的诊断鉴别价值并进行分析。方法:选取2015年1月至2017年1月我院收治的经病理诊断确诊的良性甲状腺结节以及恶性甲状腺结节患者各51例,分别对所有患者进行超声弹性成像以及血清TSH检测。分析两种检测方式单独诊断以及联合检测的结果,并与病理结果进行对比。结果:恶性结节组患者血清TSH水平为(6.2±0.2)mIU·L-1,高于良性结节组的(2.6±0.2)mIU·L-1,具有显著性差异(P < 0.05)。良性结节超声弹性成像评分为1分的人数占比为54.90%(28/51),高于恶性结节的0.00%(0/51),而评分为3分的人数占比为9.80%(5/51),低于对照组的92.16%(47/51),均具有显著性差异(均P < 0.05)。以病理检测结果为标准,联合诊断的真阳性率与真阴性率分别为94.12%(48/51)、96.08%(49/51),均高于TSH诊断以及超声弹性成像诊断,均具有显著性差异(均P < 0.05)。超声弹性成像联合TSH诊断良恶性甲状腺结节的灵敏度、特异性以及准确度分别为94.12%、96.08%以及95.10%,均高于TSH诊断以及超声弹性成像诊断,均具有显著性差异(均P < 0.05)。结论:超声弹性成像联合TSH检测诊断良恶性甲状腺结节的灵敏度、特异性以及准确度均十分显著,值得临床推广应用。

Objective: To study the ultrasound elastography in combination with TSH testing differential value to the diagnosis of patients with benign and malignant thyroid nodules and analyzed.Methods: From January 2015 to January 2017, our hospital was confirmed by pathological diagnosis of benign and malignant thyroid nodules in patients with thyroid nodule, 51 cases were respectively the ultrasound elasticity imaging in all patients, and serum TSH test. The individual diagnosis and the testing results were analyzed and the pathological results were compared.Results: Serum TSH level in patients with malignant nodules group for (6.2±0.2) mIU·L-1, higher than that of benign nodules group (2.6±0.2) mIU·L-1, with a significant difference (P<0.05). 54.90% (28/51) patients with benign nodule showed ultrasound elasticity imaging score of 1, was higher than that of malignant nodules of 0.00% (0/51), 9.80% (5/51) of the patients were rated a score of 3 which was lower than that of the control group 92.16%(47/51), all had significant differences (all P<0.05).Joint diagnosis basied on testing results of pathology. True positive rate and negative rate was 94.12% (48/51), 96.08% (49/51)higher than TSH diagnosis and ultrasound elasticity imaging diagnosis, with significant differences (all P<0.05).Joint TSH ultrasound elasticity imaging in the diagnosis of benign and malignant thyroid nodules of the sensitivity, specificity and accuracy were 94.12%, 96.08% and 95.10% respectively, and were higher than TSH diagnosis and ultrasound elasticity imaging diagnosis, had significant differences (all P<0.05).Conclusion: Ultrasound elastography in combination with TSH test in the diagnosis of benign and malignant thyroid nodules has a very good sensitivity, specificity and accuracy, worthy of clinical popularization and application.

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