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药物涂层球囊治疗急性冠脉综合征的系统评价
作者:庞思1 2  陈忠3  朱孔博1  何砚如1  Gondo Esther Kema Hawa1  章晓国1  童嘉毅1  马根山1  陈立娟1 
单位:1. 东南大学 医学院, 东南大学附属中大医院 心内科, 江苏 南京 210009;
2. 湖南省湘潭市中心医院 心内科, 湖南 湘潭 411100;
3. 上海市第六人民医院 心内科, 上海 200000
关键词:药物涂层球囊 急性冠脉综合征 经皮冠状动脉介入治疗 裸金属支架 
分类号:R543.3
出版年·卷·期(页码):2018·37·第一期(31-34)
摘要:

目的:系统评价急性冠脉综合征患者应用药物涂层球囊的疗效和安全性。方法:计算机检索Pubmed、Cochrane图书馆、EMbase、中国知网、万方数据库和中国生物医学数据库,由2名研究员独立按照纳入排除标准进行文献筛选和资料提取。结果:纳入DEB-AMI、Besic KM等、PEBSI共3项随机对照研究,其药物涂层球囊联合裸金属支架治疗的靶病变血运重建率分别为23.9%、19.5%、1.8%,主要不良心脏事件率分别为23.9%、24.4%、3.6%。此外纳入PAPPA、Ho HH等、Mahmood Zuhdi AS等、Nanolute共4篇队列研究,单纯药物涂层球囊治疗的靶病变血运重建率分别为3%、0、1.2%、5.2%。结论:药物涂层球囊可作为急性冠脉综合征的有效治疗方案,但其最佳治疗方案尚需更多大样本随机研究数据支持。

参考文献:

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