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锌指蛋白KLF12的功能研究进展
作者:丁艺1  丁玲2  程子芸1  周怀君1 2 
单位:1. 东南大学 医学院, 江苏 南京 210009;
2. 南京大学附属鼓楼医院 妇产科, 江苏 南京 210008
关键词:Krüppel样因子12 肾脏发育 脂代谢 蜕膜化 肿瘤 文献综述 
分类号:R34
出版年·卷·期(页码):2017·36·第六期(1036-1039)
摘要:

Krüppel样因子12(KLF12)是Krüppel样因子(KLF)家族成员之一,作为真核生物的转录因子,它参与肾脏发育,脂代谢,子宫内膜蜕膜化,肿瘤细胞增殖、侵袭、失巢凋亡等多种生物学进程。作者对KLF12在以上生物学进程中的研究进展作一综述,为进一步探究KLF12参与疾病发生、发展的分子机制提供理论基础,也为KLF12可能作为判断肿瘤预后新的分子标志物和治疗靶点提供理论依据。

参考文献:

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