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应用组织追踪技术分析健康人左心室心肌力学参数
作者:瞿洋洋1 2  PAUL Jan2  BUCKERT Dominik2  朱建3  马根山1 3  RASCHE Volker2 
单位:1. 东南大学 医学院, 江苏 南京 210009;
2. 乌尔姆大学医院 内科Ⅱ, 德国 乌尔姆 89081;
3. 东南大学附属中大医院 心血管内科, 江苏 南京 210009
关键词:心脏磁共振 组织追踪技术 应变 位移 扭转 
分类号:R540.4
出版年·卷·期(页码):2017·36·第三期(456-461)
摘要:

目的:分析健康成年人左心室整体和局部心肌力学参数及性别差异。方法:连续选取2015年10月至2016年8月于乌尔姆大学医院进行1.5 T心脏磁共振检查的健康成年男、女性各50名。进行稳态自由进动序列成像并半自动地勾画出左心室心内、外膜位置后,使用组织追踪技术测量左心室整体和局部(基底段、中间段和心尖段)心肌在径向、周向和纵向的应变、应变率、位移、位移速度、扭转和扭转率峰值,采用t检验或非参数检验比较性别差异。结果:(1)女性整体和局部心肌应变、应变率的峰值水平均高于男性;(2)女性中间段心肌纵向位移的峰值水平高于男性;(3)女性整体和中间段心肌纵向位移速度的峰值水平高于男性;(4)扭转和扭转率均未见显著性别差异。结论:女性左心室整体和局部的部分力学参数水平高于男性。

Objective:To analyze global and regional values as well as gender differences of left ventricular mechanical parameters in healthy adults. Methods:One hundred healthy volunteers(50 males/females)undergoing 1.5 T cardiac magnetic resonance in University Hospital of Ulm from October 2015 to August 2016 were selected continuously. After image acquisition with steady-state free precession sequence and delineation of endo-and epicardium semiautomatically, global and regional(basal, middle, apical)peak values of strain, strain rate, displacement, velocity, torsion and torsion rate were measured by tissue tracking technique in radial, circumferential and longitudinal directions respectively. Gender differences of these parameters were tested by t-test or non-parametric test. Results:The absolute values of global and regional peak strain and strain rate, mid-ventricular peak longitudinal displacement and absolute value of global and mid-ventricular peak longitudinal velocity in females were higher than those in males. No gender differences existed in torsion and torsion rate. Conclusion:Absolute values of several global and regional mechanical parameters are higher in females than those in males.

参考文献:

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