Objective:To explore the impact of procalcitonin(PCT)on contrast-induced nephropathy(CIN)after percutaneous coronary intervention(PCI)in patients with acute coronary syndrome(ACS). Methods:Two hundred and sixty patients undergoing PCI in the cardiology department of our hospital were enrolled in this study. Patients were divided into high-level group(PCT>0.5 ng·ml-1)and low-level group(PCT ≤ 0.5 ng·ml-1)according to PCT tertiles on admission to investigate the influence of PCT level on the incidence of CIN after PCI and its influencing factors. Results:CIN occurred in 22(8.5%)of 260 enrolled patients, and the incidence of CIN in high-level group(12.3%)was significantly increased compared with that in the low-level group(4.6%)(P=0.026). Multivariate Logistic regression analysis found that PCT>0.5 ng·ml-1 was an independent risk factor of CIN after adjustment for age, diabetes, hyperlipidemia, hs-CRP, eGFR, LVEF and hydration confounders(OR=1.6, 95%CI 1.2-5.31, P=0.032). Conclusion:High levels of PCT may increase the occurrence of CIN after PCI in patients with ACS. |
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