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外泌体在卵巢癌中的研究进展
作者:李玉娟1  赵树立2  谢静燕1 
单位:1. 南京医科大学附属南京医院 妇科, 江苏 南京 210006;
2. 南京医科大学附属南京医院 中心实验室, 江苏 南京 210006
关键词:外泌体 卵巢癌 综述 
分类号:R737.31
出版年·卷·期(页码):2017·36·第二期(282-285)
摘要:

卵巢癌是死亡率居首位的女性生殖系统恶性肿瘤。外泌体是由细胞内多囊泡与细胞膜融后释放到细胞外环境中的一种直径在30~100 nm的小囊泡。越来越多的研究发现外泌体是细胞间通讯的关键因子,在肿瘤细胞及肿瘤微环境的物质和信号交流中发挥重要作用。外泌体在卵巢癌的发生发展中亦有重要的调控作用,可能成为卵巢癌诊断和治疗的新靶点。

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