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感染后肠易激综合征动物模型研究进展
作者:臧凯宏1 2  秦红岩3 
单位:1. 甘肃中医药大学 药学院, 甘肃 兰州 730000;
2. 甘肃中医药大学 甘肃省中药药理与毒理学 重点实验室, 甘肃 兰州 730000;
3. 兰州大学第一医院 药剂科, 甘肃 兰州 730000
关键词:感染后肠易激综合征 炎症后肠易激综合征 动物模型 文献综述 
分类号:R574.4
出版年·卷·期(页码):2016·35·第四期(598-601)
摘要:

感染后肠易激综合征(PI-IBS)是肠易激综合征(IBS)的一种亚型。目前PI-IBS造模方法主要包括感染后IBS和炎症后IBS两大类。感染后IBS主要通过感染细菌或寄生虫诱导,炎症后IBS主要通过三硝基苯磺酸、葡聚糖硫酸钠、脱氧胆酸、乙酸等化学试剂诱导。作者就PI-IBS动物模型的研究及其进展作一综述,分析不同PI-IBS动物模型制备方法的优点与不足,以期为PI-IBS发病机制研究及治疗药物开发提供参考。

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