[1] ZHANG L,WANG F,WANG L,et al.Prevalence of chronic kidney disease in China:a cross-sectional survey[J].Lancet,2012,379(9818):815-822.
[2] FINE L G,BANDYOPADHAY D,NORMAN J T.Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia[J].Kidney Int,2000,57:S22-S26.
[3] MIMURA I,NANGAKU M.The suffocating kidney:tubulointerstitial hypoxia in end-stage renal disease[J].Nat Rev Nephrol,2010,6:667-678.
[4] JOHNSON A,DIPIETRO L A.Apoptosis and angiogenesis:an evolving mechanism for fibrosis[J].FASEB J,2013,27(10):3893-3901.
[5] BROWNING E A,CHATTERJEE S,FISHER A B.Stop the flow:a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endothelium[J].Annu Rev Physiol,2012,74:403-424.
[6] MAGGIORANI D,DISSARD R,BELLOY M,et al.Shear stress-induced alteration of epithelial organization in human renal tubular cells[J].PLoS One,2015,10(7):e0131416.
[7] 王静,刘必成.周细胞在肾脏纤维化形成中作用的研究进展[J].东南大学学报:医学版,2013,32(4):506-510.
[8] ROJAS A,CHANG F C,LIN S L,et al.The role played by perivascular cells in kidney interstitial injury[J].Clin Nephrol,2012,77(5):400-408.
[9] BIELESZ B,SIRIN Y,SI H,et al.Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans[J].J Clin Invest,2010,120(11):4040-4054.
[10] FABIAN S L,PENCHEV R R,STJACQUES B,et al.Hedgehog-Gli pathway activation during kidney fibrosis[J].Am J Pathol,2012,180(4):1441-1453.
[11] WUC F,CHIANG W C,LAI C F,et al.Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis[J].Am J Pathol,2013,182(1):118-131.
[12] YANG L,BESSCHETNOVA T Y,BROOKS C R,et al.Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury[J].Nat Med,2010,16(5):535-543.
[13] LI L,ZEPEDA-OROZCO D,BLACK R,et al.Autophagy is a component of epithelial cell fate in obstructive uropathy[J].Am J Pathol,2010,176(4):1767-1778.
[14] CAMPANHOLLE G,LIGRESTI G,GHARIB S A,et al.Cellular mechanisms of tissue fibrosis.3.Novel mechanisms of kidney fibrosis[J].Am J Physiol Cell Physiol,2013,304(7):C591-C603.
[15] SHIBUYA M.Vascular endothelial growth factor and its receptor system:physiological functions in angiogenesis and pathological roles in various diseases[J].J Biochem,2013,153(1):13-19.
[16] PHNG L K,GERHARDT H.Angiogenesis:a team effort coordinated by notch[J].Dev Cell,2009,16(2):196-208.
[17] LANAHAN A A,HERMANS K,CLAES F,et al.VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis[J].Dev Cell,2010,18(5):713-724.
[18] SITOHY B,NAGY J A,DVORAK H F.Anti-VEGF/VEGFR therapy for cancer:reassessing the target[J].Cancer Res,2012,72(8):1909-1914.
[19] SEMENZA G L.Oxygen sensing,homeostasis,and disease[J].N Engl J Med,2011,365(6):537-547.
[20] PARDALI E,GOUMANS M J,TEN DIJKE P.Signaling by members of the TGF-β family in vascular morphogenesis and disease[J].Trends Cell Biol,2010,20(9):556-567.
[21] SEMENZA G L.Oxygen sensing,hypoxia-inducible factors,and disease pathophysiology[J].Annu Rev Pathol,2014,9:47-71.
[22] MIMEAULT M,BATRA S K.Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer-and metastasis-initiating cells[J].J Cell Mol Med,2013,17(1):30-54.
[23] PARDALI E,GOUMANS M J,TEN DIJKE P.Signaling by members of the TGF-beta family in vascular morphogenesis and disease[J].Trends Cell Biol,2010,20(9):556-567.
[24] BASILE D P,SUTTON T A.Activated pericytes and the inhibition of renal vascular stability:obstacles for kidney repair[J].J Am Soc Nephrol,2012,23(5):767-769.
[25] CHADE A R.Renovascular disease,microcirculation,and the progression of renal injury:role of angiogenesis[J].Am J Physiol Regul Integr Comp Physiol,2011,300(4):R783-R790. |
