目的:分析呼吸重症监护病房患者贫血的危险性和医源性失血与贫血的关系。方法:回顾分析2011-2014年我科监护病房住院时间大于等于7 d的非明显出血、造血障碍的患者,统计其抽血量和血红蛋白的值。结果:贫血率为71.8%(244/340)。血液血红蛋白平均下降幅度为(5.9±17.2) g·L-1,存活组出院时的血红蛋白高于死亡组(P<0.05),贫血与APACHEⅡ评分相关。血红蛋白日变化与日抽血量呈负相关,抽血量越大的组,血红蛋白下降越明显,日抽血量2 ml以下组血红蛋白的下降不明显。结论:患者的诊断性失血与贫血相关,小于2 ml的日抽血对患者血红蛋白影响不明显,贫血与病情危重、预后不良相关。 |
[1] 王海旭,吴建峰,黄丽丽,等.上海市57949名健康体检者贫血情况调查[J].东南大学学报:医学版,2015,34(3):380-382.
[2] 陈洁,郑曼,张萍,等.关节置换术围术期血液丢失影响因素的探讨[J].东南大学学报:医学版,2011,30(5):713-716.
[3] AHSEN N,MULLER C,SERKE S,et al.Important role of nondiagnostic blood loss and blunted erythropoietic response in the anemia of medical intensive care patients[J].Crit Care Med,1999,27:2630-2639.
[4] VINCENT J L,BARON J F,REINHART K,et al.Anemia and blood transfusion in critically ill patients[J].JAMA,2002,288(12):1499-1507.
[5] TINMOUTH A T,MCINTYRE L A,FOWLER R A.Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients[J].CMAJ,2008,178(1):49-57.
[6] NEVINS M L,EPSTEIN S K.Predictors of outcome for patients with COPD requiring invasive mechanical ventilation[J].Chest,2001,119(6):1840-1849.
[7] MERLANI P,GARNERIN P,DIBY M,et al.Quality improvement report:linking guideline to regular feedback to increase appropriate requests for clinical tests:blood gas analysis in intensive care[J].BMJ,2001,323(7313):620-624.
[8] THAVENDIRANATHAN P,BAGAI A,EBIDIA A,et al.Do blood tests cause anemia in hospitalized patients? The effect of diagnostic phlebotomy on hemoglobin and hematocrit levels[J].J Gen Intern Med,2005,20(6):520-524.
[9] ANDREWS T,WATERMAN H,HILLIER V.Blood gas analysis:a study of blood loss in intensive care[J].J Adv Nurs,1999,30(4):851-857.
[10] CHANT C,WILSON G,FRIEDRICH J O.Anemia,transfusion,and phlebotomy practices in critically ill patients with prolonged ICU length of stay:a cohort study[J].Crit Care,2006,10(5):R140.
[11] HASHIMOTO F.Bleeding less for diagnostics[J].JAMA,1982,248(2):171.
[12] ALAZIA M L,COLAVOLPE J C,BOTTI G,et al.Blood loss from diagnostic laboratory tests performed in intensive care units.Preliminary study[J].Ann Fr Anesth Reanim,1996,15(7):1004-1007. |