[1] GRAY C S,HILDRETH A J,SANDERCOCK P A,et al.Glucose-potassium-insulin infusions in the management of post-stroke hyperglycemia:the UK glucose insulin in stroke trail(GIST-UK)[J].Lancet Neurol,2007,6(5):397-406.
[2] KLEMENS W,FRANK S,TESSA O,et al.Neuroanatomic correlates of poststroke hyperglycemia[J].Ann Neurol,2015,77(2):262-268.
[3] READ J L,CHENG E Y.Intensive insulin therapy for acute hyperglycemia[J].AACN Adv Crit Care,2007,18:200-212.
[4] BRUNO A,LEVINE S R,FRANKEL M R,et al.Admission glucose level and clinical outcomes in the NINDS rt-PA stroke trail[J].Neurology,2002,59(5):669-674.
[5] NARDI K,MILIA P,EUSEBI P,et al.Predictive value of admission blood glucose level on short-term mortality in acute cerebral ischemia[J].Diabetes Complications,2012,26(2):70-76.
[6] FANG Y,ZHANG S,WU B,et al.Hyperglycemia in acute lacunar stroke:a Chinese hospital-based study[J].Diab Vasc Dis Res,2013,10(3):216-221.
[7] UYTTENBOOGAART M,KOCH M W,STEWART R E,et al.Moderate hyperglycemia is associated with favourable outcome in acute lacunar stroke[J].Brain,2007,130(Pt6):1626-1630.
[8] KES V B,SOLTER V V,SUPANC V,et al.Impact of hyperglycemia on ischemic stroke mortality in diabetic and non-diabetic patients[J].Ann Saudi Med,2007,27(5):352-355.
[9] CAPES S E,HUNT D,MALMBERG K,et al.Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients:a systematic overview[J].Stroke,2001,32(10):2426-2432.
[10] POPPE A Y,MAJUMDAR S R,JEERAKATHIL T,et al.Admission hyperglycemia predicts a worse outcome in stroke patients treated with intravenous thrombolysis[J].Diabetes Care,2009,32(4):617-622.
[11] AHMED N,DAVALOS A,ERIKSSON N,et al.Association of admission blood glucose and outcome in patients treated with intravenous thrombolysis:results from the safe implementation of treatments in stroke international stroke thrombolysis register(SITS-ISTR)[J].Arch Neurol,2010,67(9):1123-1130.
[12] WHITELEY W N,SLOT K B,FERNANDES P,et al.Risk factors for intracranial hemorrhage in acute ischemic stroke patients treated with recombinant tissue plasminogen activator:a systematic review and meta-analysis of 55 studies[J].Stroke,2012,43(11):2904-2909.
[13] HACKE W,KASTE M,BLUHMKI E,et al.Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke[J].N Engl J Med,2008,359(13):1317-1329.
[14] 吴翠翠,牛小媛.不同时间窗rt-PA溶栓对糖尿病合并脑梗死大鼠的疗效研究[J].中西医结合心脑血管病杂志,2012,10(9):1096-1098.
[15] ANDERSON R E,TAN W K,MARTIN H S,et al.Effects of glucose and PaO2 modulation on cortical intracellular acidosis,NADH redox stae and infarction in the ischemic penumbra[J].Stroke,1999,30(1):160-170.
[16] BERTHET C,LEI H,THEVENRT J,et al.Neuroprotective role of lactate after cerebral ischemia[J].J Cereb Blood Flow Metab,2009,29(11):1780-1789.
[17] TANG H,ZHANG S,YAN S,et al.Unfavorable neurological outcome in diabetic patients with acute ischemic stroke is associated with incomplete recanalization after intravenous thrombolysis.J Neurointerv Surg.
[2015] .http://www.ncbi.nlm.nih.gov/pubmed/25735852.
[18] SENERS P,TURC G,OPPENHEIM C,et al.Incidence,causes and predictors of neurological deterioration occurring within 24h fllowing acute ischemic stroke:a systematic review with pathophysiological implications[J].J Neurol Neurosurg Psychiatry,2015,86(1):87-94.
[19] WON S J,TANG X N,SUH S W,et al.Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by increasing superoxide production[J].Ann Neurol,2011,70(4):583-590.
[20] GENTILE N T,SEFTCHICK M W,HUYNH T,et al.Decreased mortality By normalizing blood glucose after acute ischemic stroke[J].Acad Emerg Med,2006,13(2):174-180.
[21] FAX X,NING M,LO E H,et al.Early insulin glycemic control combined with tPA thrombolysis reduces acute brain tissue damages in a focal embolic stroke model of diabetic rats[J].Stroke,2013,44(1):255-259.
[22] GARG R,CHAUDHURI A,MUNSCHAUER F,et al.Hyperglycemia,insulin,and acute ischemic stroke:a mechanistic justification for a trail of insulin infusion therapy[J].Stroke,2006,37(1):267-273.
[23] STASZEWSKI J,BRODACKI B,KOTOWICZ J,et al.Intravenous insulin therapy in the maintenance of strict glycemic control in nondiabetic acute stroke patients with mild hyperglycemia[J].J Stroke Cerebrovasc Dis,2011,20(2):150-154.
[24] BELLOLIO M F,GILMORE R M,GANTI L,et al.Insulin for glycemic control in acute ischaemic stroke.Cochrane Database Syst Rev.[2015-04-01].http://www.ncbi.nlm.nih.gov/pubmed/24453023.
[25] NTAIOS G,PAPAVASILEIOU V,BARGIOTA A,et al.Intravenous insulin treatment in acute stroke:a systematic review and meta-analysis of randomized controlled trails[J].Int J Stroke,2014,9(4):489-493.
[26] KRAMER A H,ROBERTS D J,ZYQUN D A.Optimal glycemic control in neurocritical care patients:a systematic review and meta-analysis[J].Crit Care,2012,16(5):203-216.
[27] NIELSEN S T,KROQH-MADSEN R,MOLLER K,et al.Glucose metabolism in critically ill patients:are incretins an important player?[J].J Intensive Care Med,2015,30(4):201-208.
[28] 王璠璠,卢海英,刘莉洁.胰高血糖素样肽-1的研究进展[J].东南大学学报:医学版,2014,33(2):200-206.
[29] SATO K,KAMEDA M,YASUHARA T,et al.Neuroprotective effects of liraglutide for stroke model of rats[J].Int J Mol Sci,2013,14(11):21513-21524.
[30] LI W A,MOORELANGSTON S,CHAKRABORTY T,et al.Hyperglycemia in stroke and possible treatments[J].Neurol Res,2013,35(5):479-491. |
