糖尿病前期人群血脂异常及其危险因素分析-东南大学学报医学版

糖尿病前期人群血脂异常及其危险因素分析

单位：1. 东南大学公共卫生学院, 江苏南京 210009;
2. 江苏省疾病预防控制中心慢性非传染性疾病防制所, 江苏南京 210009

分类号：R587.1

出版年·卷·期（页码）：2015·34·第五期（749-753）

摘要：

目的:了解糖尿病前期人群血脂异常及其危险因素,为糖尿病和血脂异常防治提供科学依据。方法:采用分层整群随机抽样方法抽取8 400名调查对象,调查该人群中糖尿病前期者血脂异常分布情况及其影响因素。结果:空腹血糖受损(IFG)、糖耐量减低(IGT)和IFG合并IGT 3组糖尿病前期人群血脂异常率分别为35.1%、35.9%和45.9%,3组间血脂异常率差异有统计学意义(P=0.003)。多因素Logistic回归分析显示,地处农村、每日静坐时间5 h以上是IFG人群血脂异常的危险因素,随着舒张压或腰围的增加,该人群血脂异常的风险也将增加;高中以上文化、高血压、超重和肥胖是IGT人群血脂异常的危险因素,饮酒是其保护因素;超重和肥胖是IFG合并IGT人群血脂异常的危险因素。结论:糖尿病前期人群血脂异常率较高,不同类型糖尿病前期者血脂异常率不同;超重、肥胖、高腰围和高血压是糖尿病前期人群血脂异常的重要危险因素;应采取针对性的措施及时干预不同类型糖尿病前期人群的血脂异常。

Objective: Study on the dyslipidemia and its risk factors in pre-diabetes, and to provide evidences for the diabetes and dyslipidemia control and treatment. Methods: 8 400 residents were selected by stratified cluster random sampling,and finally the pre-diabetes of the total residents were surveyed using standardized questionnaires. One-way anova and Logistic regression methods were used to analyze the distribution of dyslipidemia and related risk factors. Results: The prevalence of dyslipidemia in IFG, IGT, and IFG+IGT group were 35.1%, 35.9%, and 45.9% respectively, and the prevalence were significantly different among the three groups(P=0.003). The results of binary Logistic analysis indicated that living in rural areas,sitting over five hours daily were the risk factors of dyslipidemia in IFG group; and with the increase of diastlic pressure and large waist circumstance, the risk of dyslipidmia in the group are likely to rise. in those had high school or higher degree, hypertension, overweight and obesity were risk factors of dyslipidemia in IGT group, while drinking liquor was a protective factor; staying overweight and obesity were risk factors of dyslipidemia in IFG+IGT group. Conclusion: The prevalence of dyslipidemia in pre-diabetes is higher than that in general population, and also there were significant differences in different types of pre-diabetes. The timely targeted effective measures should be taken to intervene the dyslipidemia for thepre-diabetes.

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