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非高密度脂蛋白胆固醇在冠心病风险评估中的价值
作者:张娜娜1  冯燕娴2 
单位:1. 蚌埠医学院, 安徽 蚌埠 233000;
2. 蚌埠医学院附属蚌埠市第三人民医院 心内科, 安徽 蚌埠 233000
关键词:冠心病 非高密度脂蛋白胆固醇 低密度脂蛋白胆固醇 风险评估 文献综述 
分类号:R541.4
出版年·卷·期(页码):2015·34·第三期(462-465)
摘要:

近年来,非高密度脂蛋白胆固醇(non-HDL-C)致动脉粥样硬化(AS)的作用越来越受到关注,以往在国内外有关血脂异常的管理指南中,均将低密度脂蛋白胆固醇(LDL-C)视为致AS的主要因素以及进行调脂治疗的第一指标.国内外相关研究比较了non-HDL-C与LDL-C对冠心病发病的预测作用,认为non-HDL-C评估冠心病危险的意义明显优于LDL-C.作者就non-HDL-C在冠心病风险评估中的价值作一综述.

参考文献:

[1] NAKAMURA M,KOYAMA I,ISO H,et al.Measurement performance of reagent manufacturers by Centers for Disease Control and Prevention/Cholesterol Reference Method Laboratory Network lipid standardization specified for metabolic syndrome-focused health checkups program in Japan[J].J Atheroscler Thromb,2009,16(6):756-763.
[2] KITAMURA A,NODA H,NAKAMURA M,et al.Association between non-high-density lipoprotein cholesterol levels and the incidence of coronary heart disease among Japanese:the circulatory risk in communities study(CIRCS)[J].J Atheroscler Thromb,2011,18(6):454-463.
[3] 吴炯,郭玮,潘柏中,等.冠状动脉病变时非高密度脂蛋白胆固醇的临床应用[J].检验医学,2006,21(4):316-319.
[4] SASAKI J,YOKOYAMA M,MATSUZAKI M,et al.Relationship between coronary artery disease and non-HDL-C,and effect of highly purified EPA on the risk of coronary artery disease in hypercholesterolemic patients treated with statins: sub-analysis of the Japan EPA Lipid Intervention Study (JELIS)[J].J Atheroscler Thromb,2012,19(2):194-204.
[5] 方瑛,陈忠,马根山,等.早发急性心肌梗死患者的临床和冠状动脉病变特点[J].现代医学,2009,37(2):129-132.
[6] 任洁,赵冬,刘静,等.非高密度脂蛋白胆固醇水平与中国人群心血管病发病危险的相关性[J].中华心血管病杂志,2010,38(10):934-938.
[7] ORAKZAI S H,NASIR K,BLAHA M,et al.Non-HDL cholesterol is strongly association with coronary artery calcification in asymptomatic individuals[J].Atherosclerosis,2009,202(1):289-295.
[8] ARSENAULT B J,RANA J S,STROES E S,et al.Beyond low-density lipoprotein ch-olesterol:respective contributions of non-high-density lipoprotein cholesterol levels,triglycerides,and the total cholesterol/high-density lipoprotein cholesterol ratio to coronary heart disease risk in apparently healthy men and women[J].J Am Coll Cardiol,2009,55(1):35-41.
[9] OKAMURA T,KOKUBO Y,WATANABE M,et al.Triglycerides and non-high-density lipoprotein cholesterol and the incidence of cardiovascular disease in an urban Japanese cohort:the Suita study[J].Atherosclerosis,2010,209:290-294.
[10] ROBINSON J G,WANG S,SMITH B J,et al.Meta-analysis of the relationship between non-high-density lipoprotein cholesterol reduction and coronary heart disease risk[J].J Am Coll Cardiol,2009,53(4):316-322.
[11] KOKUBO Y,WATANABE M.Low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol and the incidence of cardiovascular disease in an urban Japanese cohort study: the Suita study[J].Atherosclerosis,2009,203(2): 587-592.
[12] TANABE N,ISO H,OKADA K,et al.Serum total and non-high-density lipoprotein cholesterol and the risk prediction of cardiovascular events-the JALS-ECC[J].Circ J,2010,74(7):1346-1349.
[13] 严字斐,曹国君.血清非高密度脂蛋白胆固醇在冠心病诊断中的临床价值[J].中国现代医药杂志,2013,15(6):9-12.
[14] ROBINSON J G,WANG S,JACOBSON T A.Meta-analysis of comparison of effectiv-eness of lowering apolipoprotein B versus low-density lipoprotein cholesterol and non high-density lipoprotein cholesterol for cardiovascular risk reduction in randomized trials[J].Am J Cardiol,2012,110(10):1468-1476.
[15] RAY K K,CANNON C P,CAIRNS R,et al.Prognostic utility of ApoB/AI,total chole-sterol/HDL,non-HDL cholesterol,or hs-CRP as predictors of clinical risk in patients receiving statin therapy after acute coronary syndromes:results from PROVE IT-TIMI 22[J].Arterioscler Thromb Vase Biol,2009,29(3):424-430.
[16] BOEKHOLDT S M,ARSENAULT B J,MORA M,et al.Association of LDL cholesterol,non-HDL cholesterol,and apolipoprotein B levels with risk of cardiovascular events amongpatients treated with statins:A Meta-analysis[J].JAMA,2012,307(12):1302-1309.
[17] SIMPRINI L A,VILLINES T C,RICH M,et al.The relationship between subclinical atherosclerosis,non-high-density lipoprotein cholesterol,exercise,and diet among male participants of the PACC Project[J].J Clin Lipidol,2012,6(2):174-179.
[18] 李渊,徐卫亭,陈建昌,等.非高密度脂蛋白胆固醇在老年高血压及糖尿病人群中的临床意义[J].中国心血管杂志,2011,16(5):344-347.
[19] 张鹏睿,徐援,王广,等.非高密度脂蛋白胆固醇是评价血脂异常患者心血管风险的指标[J].首都医科大学学报,2014,35(1):73-76.
[20] JACOBSON T A,ITO M K,MAKI K C,et al.National lipid association recommendations for patient-centered management of dyslipidemia:part 1-executive summary[J].J Clin Lipidol,2014,8(5):473-488.

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