>
网站首页期刊介绍通知公告编 委 会投稿须知电子期刊广告合作联系我们
最新消息:
支气管肺泡灌洗液在间质性肺疾病中的诊断价值
作者:鲁文强  岳红梅  何含  罗亚娟 
单位:兰州大学第一医院 呼吸内科, 甘肃 兰州 730000
关键词:支气管肺泡灌洗液 细胞分类 间质性肺疾病 
分类号:R563
出版年·卷·期(页码):2015·34·第二期(273-276)
摘要:

目的:研究支气管肺泡灌洗液的常规细胞分型在间质性肺疾病中的诊断价值.方法:选取我院收治的间质性肺疾病患者31例,行支气管镜活检和支气管肺泡灌洗,对灌洗液行细胞分类,综合临床表现、高分辨率CT(HRCT)及组织病理学最终诊断.结果:入组间质性肺疾病患者中诊断为特发性肺间质纤维化(IPF)13例,结缔组织相关性间质性肺炎(CTD-ILD)7例,结节病3例,隐源性机化性肺炎(COP)4例,外源性过敏性肺炎(EAA)2例,慢性嗜酸粒细胞性肺炎(CEP)2例,结论:支气管肺泡灌洗液常规细胞分型有助于间质性肺疾病的鉴别诊断.

参考文献:

[1] American Thoracic Society.European respiratory society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias[J].Am J Respir Crit Care Med,2002,165:277-304.
[2] RAGHU G,COLLARD H R,EGAN J J,et al.An official ATS/ERS/JRS/ALAT statement:idiopathic pulmonary fibrosis:evidence-based guidelines for diagnosis and management[J].Am J Respir Crit Care Med,2011,183:788-824.
[3] MEYER K C,RAGHU G,BAUGHMAN R P,et al.An official American Thoracic Society clinical practice guideline:the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease[J].European Respiratory Journal,2012,185:1004-1014.
[4] 李振华.支气管肺泡灌洗技术及临床应用.第5届中国呼吸医师论坛论文集.北京.2006:126-134.
[5] 徐健,周道银,俞靖龙,等.支气管肺泡灌洗液常规细胞形态学检查的临床应用价值评价[J].检验医学,2012,27:221-224.
[6] 苟丽霞,吴国球,范晓波,等.结缔组织生长因子单链抗体对博莱霉素诱导的小鼠肺纤维化的影响[J].东南大学学报:医学版,2010,29(2):139-143.
[7] RAGHU G,LYNCH D,GODWIN J D,et al.Diagnosis of idiopathic pulmonary fibrosis with high-resolution CT in patients with little or no radiological evidence of honeycombing:secondary analysis of a randomised,controlled trial[J].Lancet Respir Med,2014,2(4):277-284.
[8] JARA-PALOMARES L,MARTIN-JUAN J,GOMEZ-IZQUIERDO L,et al.Bronchoalveolar lavage findings in patients with diffuse interstitial lung disease:prospective study of a cohort of 562 patients[J].Archivos de Bronconeumología (English Edition),2009,45:115-121.
[9] OHSHIMO S,BONELLA F,CUI A,et al.Significance of bronchoalveolar lavage for the diagnosis of idiopathic pulmonary fibrosis[J].Am J Respir Crit Care Med,2009,179:1043-1047.
[10] WELKER L,JÖRRES R,COSTABEL U,et al.Predictive value of BAL cell differentials in the diagnosis of interstitial lung diseases[J].Eur Respir J,2004,24:1000-1006.
[11] JOHKOH T,MÜLLER N L,CARTIER Y,et al.Idiopathic interstitial pneumonias:diagnostic accuracy of thin-section CT in 129 patients[J].Radiology,1999,211:555-560.
[12] POLETTI V,CAZZATO S,MINICUCI N,et al.The diagnostic value of bronchoalveolar lavage and transbronchial lung biopsy in cryptogenic organizing pneumonia[J].Eur Respir J,1996,9:2513-2516.
[13] MEYER K C,RAGHU G.Bronchoalveolar lavage for the evaluation of interstitial lung disease:is it clinically useful?[J].Eur Respir J,2011,38:761-769.
[14] COSTABEL U,GUZMAN J,BONELLA F,et al.Bronchoalveolar lavage in other interstitial lung diseases[J].Semin Respir Crit Care Med,2007,28:514-524.

服务与反馈:
文章下载】【发表评论】【查看评论】【加入收藏
提示:您还未登录,请登录!点此登录
您是第 418099 位访问者


copyright ©《东南大学学报(医学版)》编辑部
联系电话:025-83272481 83272483
电子邮件:
bjb@pub.seu.edu.cn

苏ICP备09058364