Objective: To understand the occurrence time of menstrual changes and the menopausal symptoms,and the level of understanding, use and need for knowledge regarding HRT,in order to provide the basis for reproductive health in older women. Methods: Questionnaire on women of age ≥40,with at least one ovary, who have changed menstrual cycles or menopausal symptoms. Results: The survey involved 326 cases(including 307 who never used HRT,15 frequent users and 4 who used HRT once).The mean age of the women were 49.49;the average age of menopause is 49.1;the average age of menstruation change was 45.6;the average age at which menopause symptoms appeared was 46.6. 38.6% of them had knowledge regarding HRT,44.2% believed it was necessary to treat menopausal symptoms,42.1% received hormone replacement therapy, but had their concerns about the therapy, 96.7% would like more perimenopausal health knowledge and information sought mainly through obstetrician, medical books and print media. The percentage of use of hormone replacement therapy was 5.83%. Conclusion: The menopausal and hormone replacement therapy knowledges are of low awareness among older women,we should focus more on education,while providing convenient medical support,to further improve the health level and living quality of older women.