目的: 通过对类风湿关节炎(RA)膝关节滑膜病变超声与MRI表现的对比,分析高频超声诊断RA膝关节滑膜病变与MRI的相关性.方法: 对临床确诊RA的30例患者患侧膝关节和20例正常对照者双侧膝关节行超声检查,在相同切面测量滑膜厚度,并进行对比分析.对RA组患侧膝关节行MRI检查,在超声和MRI相同的切面上观察滑膜病变情况,对比分析两种影像学检查结果.结果: RA组髌骨上、内外侧髁滑膜较对照组明显增厚(P<0.001);超声和MRI均显示滑膜增厚,超声测量的滑膜厚度与MRI测值无明显差异(P>0.1);超声与MRI对滑膜增厚分级具有较好的相关性(P<0.001).结论: 超声对膝关节类风湿性滑膜病变的检查结果与MRI具有较好的相关性,在临床应用中可作为诊断RA膝关节滑膜病变的首选检查方法. |
[1] FAUCI A S,LANGFORD C A.哈里森风湿病学[M].田新平,曾小峰,译.北京: 人民卫生出版社,2009: 74-85.
[2] ALETAHA D,NEOGI T,SILMAN A J,et al.2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism Collaborative Initiative[J].Ann Rheum Dis,2010,69(9): 1580-1588.
[3] HARTUNG W,KELLNER H,STRUNK J,et al.Development and evaluation of a novel ultrasound score for large joints in rheumatoid arthritis: one year of experience in daily clinical practice[J].Arthritis Care Res(Hoboken),2012,64(5): 675-682.
[4] COUMBARAS M,LEHIR P,SAUTET A,et al.Reactive synovitis: MRI features with arthroscopic correlation[J].Radiol,2005,86(5): 481-486.
[5] SKINNER S.MRI of the knee[J].Aust Fam Physician,2012,41(11): 867-869.
[6] BACKHAUS M,KAMRADT T,SANDROCK D,et al.Arthritis of the finger joints: a comprehensive approach comparing conventional radiography,scintigraphy,ultrasound,and contrast-enhanced magnetic resonance imaging[J].Arthritis Rheum,1999,42(6): 1232-1245.
[7] WAKEFIELD R,GOH E,CONAGHAN P,et al.Musculoskeletal ultrasonography in Europe results of a rheumatologist-based survey at a EULAR meeting[J].Rheumatology,2003,42: 1251-1253.
[8] 李文春,李振强.膝关节滑膜囊的应用解剖[J].中国临床解剖学杂志,1994,12(3): 189-191.
[9] VLAD V,BERGHEA F,LIBIANU S,et al.Ultrasound in rheumatoid arthritis: volar versus dorsal synovitis evaluation and scoring[J].BMC Musculoskelet Disord,2011,3(12): 124.
[10] WALTHER M,HARMS H,KRENN V,et al.Synovial tissue of the hip at power Doppler US: Correlation between vascularity and power Doppler US signal[J].Radiology,2002,225(1): 225-231.
[11] 邱逦,罗燕,彭玉兰.超声对于类风湿性关节炎膝关节滑膜病变的研究[J].中国医学影像技术,2005,21(11): 1372-1374. |