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卵巢癌肿瘤细胞减灭术的危险因素分析
作者:赵一兵  吴强  曲军卫  房志萍 
单位:江苏省肿瘤医院 妇瘤外科, 江苏 南京 210009
关键词:卵巢癌 肿瘤细胞减灭术 危险因素 
分类号:R737.31
出版年·卷·期(页码):2014·33·第六期(696-698)
摘要:

目的: 调查与卵巢癌肿瘤细胞减灭术有关的危险因素.方法: 收集2010年1月至2013年12月入院的238例行肿瘤细胞减灭术病人的临床资料,统计分析可能导致手术并发症的因素.结果: 白蛋白<35 g·L-1、血红蛋白<8 g·L-1、术中出血>400 ml、合并症、腹主动脉旁淋巴结清扫和肠切除等6个因素是卵巢癌肿瘤细胞减灭术的危险因素.结论: 在准备行卵巢癌肿瘤细胞减灭术时,对以上危险因素应仔细考虑,有目的地控制相关因素,可以减少卵巢癌肿瘤细胞减灭术有关并发症的发生.

Objective: To investigate the risk factors in cytoreductive surgery. Methods: 238 cases of patients who underwent cytoreductive surgery from January 2010 to December 2013 were analysed to shed light on risk factors of postoperative complications. Results: The six risk factors we found are: albumin<35 g·L-1, hemoglobin<80 g·L-1, blooding>400 ml, complication, periaortic lymph nodes dissection and intestinal resection. Conclusion: These risk factors should be considered carefully before operations. Controlling the risk factors properly may reduce the postoperative complication rate after cytoreductivesurgery.

参考文献:

[1] HUANG C Q,FENG J P,YANG X J,et al.Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from colorectal cancer: a case-control study from a Chinese center[J].J Surg Oncol,2014,109(7): 730-739.
[2] FERRERO A,DITTO A,GIORDA G,et al.Secondary cytoreductive surgery for isolated lymph node recurrence of epithelial ovarian cancer: a multicenter study[J].Eur J Surg Oncol,2014,40(7): 891-898.
[3] PASSOT G,BAKRIN N,ROUX A S,et al.Quality of life after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy: a prospective study of 216 patients[J].Eur J Surg Oncol,2014,40(5): 529-535.
[4] ANG C,CHAN K K,BRYANT A,et al.Ultra-radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer[J].Cochranc Database Syst Rev,2011(4): CD007697.
[5] ARMSTRONG D K,COLEMAN R L,PENSON R T.Emerging therapeutic options for platinum-sensitive ovarian cancer patients[J].Clin Adv Hematol Oncol,2011,9(4 Suppl 5): 1-16.
[6] ZIGHELBOIM I,RAMIREZ P T,GAO F,et al.Retroperitoneal lymph node resection in patients with cervical cancer[J].Surg Oncol,2006,15(2): 79-83.

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