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HOXA10在妇科疾病研究中的进展
作者:李建1  周怀君2 
单位:1. 东南大学 医学院, 江苏 南京 210008;
2. 南京大学附属鼓楼医院 妇产科, 江苏 南京 210009
关键词:HOXA10 子宫内膜癌 卵巢癌 子宫内膜异位症 
分类号:R737.33;R737.31
出版年·卷·期(页码):2014·33·第五期(665-668)
摘要:

HOXA10是同源框基因家族中重要的一员,在正常人的子宫内膜腺上皮、间质细胞中均有表达,起到编码转录因子、促进细胞分化和调控胚胎发育的作用。研究表明在子宫内膜癌、卵巢癌、子宫内膜异位症及其他妇科疾病患者内膜中均检测到HOXA10的异常表达,但其具体调控机制仍然不明确。因此,针对HOXA10的深入研究为相关妇科疾病的诊断、治疗提供了新思路。

参考文献:

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