运用Logistic回归分析探讨胎儿生长受限的高危因素-东南大学学报医学版

运用Logistic回归分析探讨胎儿生长受限的高危因素

单位：厦门市妇幼保健院产前诊断中心, 福建厦门 361003

分类号：R714.43

出版年·卷·期（页码）：2014·33·第五期（619-621）

摘要：

目的：探讨胎儿生长受限的影响因素及其与妊娠结局的关联性。方法：以厦门市妇幼保健院2011年1月1日至2011年12月31日的分娩临床资料作为样本进行病例对照研究，数据经χ² 检验、独立样本t检验和多因素非条件Logistic回归进行分析。结果：胎儿生长受限的影响因素有：孕妇年龄（P=0.047，OR=0.949，CI 0.901~0.999）、贫血（P=0.008，OR=1.354，CI 0.164~0.766）、羊水过少（P=0.034，OR=2.530，CI 1.074~5.964）及胎盘异常（P=0.015，OR=2.337，CI 1.180~4.626）等。结论：贫血、胎盘异常、羊水过少是与胎儿生长受限有关的主要因素，针对相关因素积极干预有助于防治胎儿生长受限。

Objective:To study the correlated factors for fetal growth retardation (FGR) and evaluate the association between variables and pregnancy outcomes. Methods:A case-control study was conducted in this hospital of Xiamen Maternity and Child Health Care Hospital based on the data of patients treated from 1.1.2011 to 12.31.2011.Chi-square test,independent-Sample t Test and multivariable unconditional Logistic regression analysis were used to evaluate the association between variables and pregnancy outcomes. Results:According to the analysis, the factors associated with FGR were as follows:age(P=0.047,OR=0.949,CI 0.901-0.999),anemia(P=0.008,OR=1.354,CI 0.164-0.766), hypamnios(P=0.034,OR=2.530,CI 1.074-5.964 )and placental abnormality(P=0.015,OR=2.337,CI 1.180-4.626).Conclusion:Anemia, hypamnios and placental abnormality are reasons correlatted with FGR. Active prevention targeting to the above-mentioned high risk factors can reduce the occurrence of FGR.

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