肝脏功能的检测方法层出不穷，包括Child-Pugh分级、MELD评分、吲哚氰绿法、D-山梨醇法等。然而任何一种肝功能检查法尚无法单独用来评估患者的肝脏储备功能。在本文中作者将针对各种检测方法的特点，从不同方面对其进行剖析，对各种方法的意义及其在肝储备功能测定方面的应用价值作一综述，为临床肝脏储备功能的评估提供较为合理的参考。

[1] MANIZATE F,HIOTIS S P,LABOW D,et al. Liver functional reserve estimation:state of the art and relevance to local treatments[J].Oncology,2010,78(1):131-134.
[2] KAMATH P S,WIESNER R H,MALINCHOC M,et al.A model to predict survival in patients with end-stage liver disease[J].Hepatology,2001,33(2):464-470.
[3] 项灿宏,吕文平,董家鸿.肝切除前肝脏储备功能的评估[J].中国现代普通外科进展,2011,14(3):208-211.
[4] GOTTHARDT D,WEISS K H,BAUMGRTNER M,et al.Limitations of the MELD score in predicting mortality or need for removal from waiting list in patients awaiting liver transplantation[J].BMC Gastroenterology,2009,9(1):72.
[5] 董家鸿,杨世忠,段伟东,等.精准肝脏外科技术在复杂肝脏占位性病变切除中的应用[J].中华外科杂志,2009,47(21):1610-1615.
[6] MOLINO G,CAVANNA A,AVAGNINA P,et al.Hepatic clearance of D-Sorbitol:noninvasive test for evaluating functional liver flow plasma[J].Dig Dis Sci,1987,32(7):753-758.
[7] LI Y M,LV F,XU X,et al.Evaluation of liver functional reserve by combining D-sorbitol clearance rate and CT measured liver volume[J].World J Gastroenterol,2003,9(9):2092-2095.
[8] ZHENG P,WU X J,LI J S,et al.Functional hepatic flow in patients with liver cirrhosis[J].World J Gastroenterol,2004,10(6):915-918.
[9] 潘峥,吴性江,黎介寿,等.肝硬化门静脉高压症患者肝脏功能性血流量检测的临床意义[J].中华普通外科杂志,2004,199(11):653-655.
[10] MIKI K,MATSUI Y,TERUYA M,et al.Index of convexity:A novel liver function index using Tc-GSA scintigraphy[J].World J Gastroenterol,2013,19(1):92-96.
[11] 周伟平,陈汉,吴孟超.术前评价肝脏储备功能的方法与意义[J].中华肝胆外科杂志,2003,11(4):245-246.
[12] 吴邦富,林丽莉,胡品津.胰高血糖素负荷后血环磷腺普值与肝硬化患者肝功能状况的关系[J].胃肠病学,2001,6(3):190-191.
[13] 李琴,张福奎,马红,等.血清前白蛋白、胆碱酯酶及胆汁酸在评价肝硬化患者肝脏储备功能及其变化中的临床价值[J].中华肝脏病杂志,2004,3(4):195-197.
[14] 彭志平,王序.血清前白蛋白和胆碱酯酶在肝硬化患者肝储备功能评估中的应用[J].实用医学杂志,2011,27(7):1278-1279.
[15] RAVAIOLI M,GRAZI G L,PRINCIPE A,et al.Operative risk by the lidocaine test(MEGX) in resected patients for HCC on cirrhosis[J].Hepatogastroenterology,2003,50(53):1552-1555.
[16] 张珂,蒋力,穆毅,等.吲哚氰绿试验联合血栓弹力图补充Child-Pugh分级在评估门脉高压手术患者肝储备功能中的应用[J].实用医学杂志,2010,26(9):1475-1478.
[17] LEE S G,HWANG S.How I do it:assessment of hepatic functional reserve for indication ofhepatic resection[J].J Hepatobiliary Pancreat Surg,2005,12:38-43.
[18] UCHIYAMA K,MORI K,TABUSE K,et al.Assessment of liver function for successful hepatectomy in patientswith hepatocellular carcinoma with impaired hepatic function[J].J Hepatobiliary Pancreat Sci,2008,15:596-602.