布地奈德混悬液喷喉对于喉罩拔除后咽痛的疗效观察-东南大学学报医学版

布地奈德混悬液喷喉对于喉罩拔除后咽痛的疗效观察

单位：东南大学附属中大医院麻醉科, 江苏南京 210009

分类号：R619

出版年·卷·期（页码）：2014·33·第三期（332-334）

摘要：

目的：探讨布地奈德混悬液喷喉对于喉罩拔除后咽痛的疗效。方法：将90例使用喉罩的妇科和乳腺外科手术的患者，随机分为布地奈德组（A组，n=30）、生理盐水组（B组，n=30）和利多卡因组（C组，n=30）。患者完全清醒拔除喉罩后A组给予布地奈德混悬液1 ml（内含布地奈德0.5 mg）+生理盐水1 ml喷喉，B组给予生理盐水2 ml喷喉，C组给予2%利多卡因2 ml喷喉。分别记录喉罩置入的次数，喉罩置入至拔除时间，喉罩拔除后1 h（T1）、4 h（T2）、12 h（T3）、24 h（T4）的咽喉痛情况和严重程度。结果：3组患者年龄、体重、喉罩置入次数、喉罩置入至拔除时间差异无统计学意义（P>0.05）。A组与B、C两组相比在T1、T2、T3时间点疼痛分级的差异有统计学意义（P<0.05）。结论：布地奈德混悬液喷喉对于喉罩拔除后的患者可有效降低术后24 h内咽痛发生率，同时明显减轻咽痛程度。

Objective:To observe the effect of budesonide suspension spray to the throat sore after the removal of the laryngeal mask. Methods:Ninety patients scheduled for gynecological and mammary surgery with the laryngeal mask airway management, were randomly assigned into three groups:the budesonide group (group A, n=30), which received 1 ml budesonide suspension (containing 0.5 mg budesonide) and 1 ml physiological saline spray; saline group (group B, n=30), which were given 2 ml physiological saline throat spray; and lidocaine group (group C, n=30), which were administered with 2 ml 2% lidocaine spray. All the spray was given after the removal of laryngeal mask when the patients were fully awake. The number of attempts required until successful laryngeal mask insertion, the time course from LMA insertion to removal, and the severity of throat sore at 1 h (T1), 4 h (T2), 12 h (T3) and 24 h (T4) after the removal of LMA were obtained. Results:There's no significance of age, weight, the number of attempts required until successful laryngeal mask insertion and the time course from LMA insertion to removal among the three groups statistically(P>0.05). Significantly decrease of throat sore in group A was observed at T1, T2 and T3 compared to goup B and C(P<0.05). Conclusion:The incidence and severity of throat sore after removal of LMA were significantly decreased with the administration of budesonide throat spray within 24 hours postoperatively.

参考文献：

[1] ASAI T, BRIMACOMBE J.Cuff volume and size selection with the laryngeal mask[J].Anaesthesia,2000,55(12):1179-1184.
[2] SEET E, YOUSAF F, GUPTA S, et al.Use of manometry for laryngeal mask airway reduces postoperative pharyngolaryngeal adverse events:a prospective, randomized trial[J].Anesthesiology,2010,112(3):652-657.
[3] 陈燕青,王家东,徐雅男,等.布地奈德雾化吸入对全身麻醉气管插管术后咽喉部并发症的缓解作用[J].上海交通大学学报:医学版,2012,32(12):1746-1749.
[4] 宗酉明,周红梅,杜炎芳,等.利多卡因雾化吸入对气管插管时心血管反应的预防作用[J].临床麻醉学杂志,2002,18(10):556-557.
[5] 吴论,刘志群,郭能起,等.薄荷水或布地奈德雾化吸入对插管全麻患者喉部并发症的影响[J].右江民族医学院学报,2009,31(3):410-411.
[6] 于健,王立冬,薛桂芬.布地奈德治疗急性会厌炎[J].中国耳鼻咽喉头颈外科,2008,15(1):55-56.
[7] 张念凯,万秀明,黄沂传,等.布地奈德在耳鼻咽喉科疾病治疗中的应用[J].齐鲁医学杂志,2007,22(2):100-103.
[8] 吴海霞,孔静.雾化吸入布地奈德混悬液预防气管插管后咽喉部并发症疗效分析[J].中国误诊学杂志,2011,11(8):1798.
[9] 朱毅,孙培莉.激素联合支气管舒张剂雾化吸入治疗哮喘中重度急性发作疗效评价[J].东南大学学报:医学版,2011,30(6):882-885.
[10] 吴振忠,王凤娟,杨涛.2%利多卡因雾化吸入预防气管插管时心血管不良反应的临床体会[J].吉林医学,2008,29(17):1459-1460.
[11] 罗一鸣,黄志纯,孙宝宾.抗神经生长因子抗体对变应性鼻炎大鼠鼻黏膜炎症的影响[J].东南大学学报:医学版,2011,30(3):495-499.

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