Objective: To observe the clinical curative effect, survival rate and adverse reaction of advanced esophageal carcinoma, we applied different combinations of the three-dimensional conformal radiotherapy. Methods: 90 cases of advanced esophageal carcinoma confirmed by pathology were divided randomly into radiotherapy group(n=30),chemoradiotherapy group(n=30), hyperthermochemoradiotherapy group(n=30).After three months of treatment, the near future curative effect and adverse reaction were evaluated;the long-term curative effect was determined at the end of follow-up. Results: Radiotherapy group had an effective rate of 46.7%. Chemoradiotherapy group 63.3%, Hyperthermochemoradiotherapy group 86.7%, the differences among the three groups were statistically significant(P<0.05).One year survival rate in each group were 50%, 66.7%,86.7%,with statistical significance(P<0.05). The incidence of radiation esophagitis, radiation pneumonitis, bone marrow suppression of radiotherapy group was significantly lower than chemotherapy group and hyperthermochemoradiotherapy group with significant difference(P<0.05). Conclusion: Chemoradiotherapy combined with external high frequency thermotherapy in the treatment of advanced esophageal carcinoma further improves effective rate and survival rate with tolerated adverse reactions. |
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