体描仪测定哮喘儿童和成人肺功能的临床意义-东南大学学报医学版

体描仪测定哮喘儿童和成人肺功能的临床意义

单位：东南大学,附属中大医院,江苏,南京,210009

分类号：R562.25, R448

出版年·卷·期（页码）：2003·22·第六期（399-402）

摘要：

目的:探讨人体体积描记仪(人体体描仪)测定哮喘儿童和成人肺功能的临床意义.方法:采用人体体描仪测定哮喘发作期儿童及成人治疗前后的肺功能,比较第1秒用力呼气容积(FEV1)、用力呼气肺活量(FVC)、第1秒用力呼气容积占用力呼气肺活量比值(FEV1/FVC)、最大呼气流量(PEF)和用力呼气25%、50%肺活量时瞬间流量(FEF25%、FEF50%)等肺功能指标的变化幅度.结果:治疗前儿童和成人组PEF异常率分别为92.58%和86.36%,治疗后上述指标均有不同程度提高,差异显著(均为P<0.001);两组间肺功能变化幅度除PEF(P>0.05)外,FVC、FEV1、FEV1/FVC、FEF25%、FEF50%差异均有显著性(均为P<0.01).结论:采用人体体描仪进行肺功能测定有利于哮喘诊断和发作期病情评估,更适合于年长儿童肺功能指标的监测.

Objective To evaluate the clinical significance of pulmonary function with auto-body plethysmograph in children and adults with asthma.Method The pulmonary function of pretherapy and of post-treatment was evaluated with auto-body plethysmograph in children and adults with asthma, and the changes of forced expiratory volume in 1 sec (FEV 1),forced vital capacity (FVC),FEV 1/FVC,peak expiratory flow(PEF),forced mid-expiratory flow rate (FEF 25%,FEF 50%) were measured. Results 25 of 27 cases in children(92.58%) and 19 case of 22 adults (86.36%) were abnormal in PEF before treatment. The values of FEV 1,FVC,FEV 1/FVC,FEF 25%,FEF 50% in post-treatment in both groups were increased significantly(P<0.01). Conclusion Determination on pulmonary function by auto-body plethysmograph is valuable on the diagnosis and treatment of asthma.

参考文献：

[1] 中华医学会呼吸病学分会哮喘学组. 支气管哮喘防治指南(支气管哮喘的定义、诊断、治疗及教育和管理方案). 中华结核和呼吸杂志2003(3)
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