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SR蛋白研究进展
作者:王善治 袁榴娣 
单位:东南大学遗传学研究中心,遗传与发育生物学系,江苏,南京,210009
关键词:RNA结合蛋白质类 SR蛋白 RNA剪接 综述文献 
分类号:Q756, Q522.2
出版年·卷·期(页码):2003·22·第四期(279-281)
摘要:

在真核生物众多拼接因子中,SR蛋白家族是一类重要的成员,它们与一些特定的RNA序列结合,帮助识别并选择正确的5′及3′拼接位点,与其它的拼接因子共同完成拼接任务,在决定组织细胞的特异性及个体发育的阶段性方面发挥着关键作用.本文就近10年来有关SR蛋白的结构和功能的研究进展作一综述.

Among the splicing factors of eukaryon,SR protein family is very important.They are bound to some specific RNA sequences and help to recognize and select correct 5′ and 3′ splice sites,interacting with other splicing factors to finish the work.SR proteins play an important role in determination of the specificity of tissue cells and definition of the stages of individual development.

参考文献:

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[10] Longman D, JOHNSTONE I L, CACERES J F. Functional characterization of SR and SR-related genes in Caenorhabditis elegans. 2000(7)
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