Objective  To summarize clinicopathological features of well-differentiated mucoepidermoid carcinoma of parotid to raise diagnostic accuracy.Method  The clinical data and pathological features of 10 cases from January 1987 to January 2003 were reviewd.Results  Among the 10 cases,2 cases were misdiagnosed as lymph node swelling,and 4 cases were misdiagnosed as plemorphic adenoma.2 others underwent fine needle aspiration,one of which was suggestive of MEC and later confirmed by intra-operative observation and postoperative examination;the other of which,due to limited amount of aspirated cells and the operator’s inexperience,suggested benign pathological process,but later confirmed well-differentiated MEC by freezing microtomy.The tumor exhibited irregular invasive borders,and comprised mucin-filled cysts and irregular tumor nests.The tumor cells had bland nuclei,and mitotic figures were rare.Conclusions  The tumor is very likely to be misdiagnosed as pleomophic adenoma.Preoperative fine needle aspiration is helpful for early diagonosis of well-differentiated mucoepidermoid carcinoma.