Objective  To compare the curative effect of two kinds of operative therapy to congenital absence of vagina.Methods  Vaginoplasty with sigmoid was applied to 18 cases,and vulvar  inguinal skin flap transfer to 5 cases.The differences in the therapeutic effect,operation duration,bleeding,post  operative hospitalization and expenses between the two groups were compared.Results  Operation success rates were both 100%.No complications occurred. The artificial vaginal cave had enough width and depth,soft and flexible,no vaginal model needed,which enabled the patients to have normal intercourse.There was no significant difference in average time spent in operation,post  operative hospitalization and expenses(  P  >0  05).But there was more bleeding in the operation of vaginoplasty with sigmoid(  P  <0  01).Conclusion  Both methods are ideal to those who are congenitally absent of vagina.Vaginoplasty with sigmoid is superior to the other in terms of anatomy,function and vulva morphology.